They’re Everywhere!

Ever wonder what germs are? They are Microorganisms called pathogens which harbor a specific infectious agent. They are also known as biological agents such as bacteria, virus, prion, fungus, or biological toxins that cause disease.[1][2][3]

There are several ways whereby germs can invade your body; the air, bodily contact, blood exchange or the food we eat. Each has its own time frame for manifestation.
Soil contamination has the longest or most persistent potential for harboring germs other than your warm body. Once germs reach the body either through the nose, skin, gastrointestinal tract or body fluids, it is only a matter of time before they are eradicated by our immune system or surface through symptoms.

The good news is that your body contains many natural orders of defense against some of the common germs (such as Pneumocystis pneumonia) in the form of the human immune system and by some “helpful” bacteria present in your body’s normal flora (good bacteria). However, if your immune system or “good” bacteria is or becomes damaged in any way (by chemotherapy, human immunodeficiency virus (HIV), or antibiotics to name a few), germs such as bacteria that were being held at bay can proliferate and cause harm to your body. Such cases are called opportunistic infection.
In the past some germs, such as the bacterium which may have caused the Black Plague, the Variola virus, have been responsible for massive numbers of casualties and have had numerous effects on afflicted groups. Of particular note in modern times is the HIV virus, which is known to have infected several million humans globally, along with the Influenza virus.

While many medical advances have been made today to safeguard against infection by germs, through the use of vaccination, antibiotics, and fungicide, germs continue to threaten human life. While social advances such as food safety, Dietary Supplement safety, hygiene, and water treatment have reduced the threat from some germs, some still remain. It should also be mentioned that not all germs are bad or negative.

As recently as 1-3-11 we hear about germs in the news. The latest news is centered on “Germs found in Restaurants.” What a surprise!  Of course, germs are everywhere and have been since the beginning of time. Ever wondered what those “Big Letters” in the windows of restaurants mean? This is a letter-grading system set by the health & sanitation departments in most cities. Customers may find any of three grades in the window: a favorable “A,” passing “B” or disastrous “C.”

Giving consumers more information will help make our restaurants safer and cleaner. The signs just might be an indication of where certain germs may be lurking, so pay attention. Los Angeles, which has used a similar evaluation method for more than a decade now, has seen a 13 percent decline in food-borne illnesses because of this letter grading system.
The top 5 most popular areas germs are spread throughout the year are:

• Hospitals
• Airplanes
• Buses
• Door handles & counter tops
• Money exchange.

As you see it’s not always altogether possible to avoid germs. The best way is to avoid them is to:

• Wash your hands regularly
• Use hand sanitizers whenever appropriate
• Take Vitamin D3 (5,000 UI approx.) daily
• Get plenty of rest

If you think you have come in contact with germs such as flu, colds, even food poisoning etc…or would like to increase your odds of not getting them-Use

• The Original Olive Leaf Extract
• Beta 1, 3-D Glucan

They both are used historically for such.  Check out our new discounts for 2011 and order yours today.

Best of health to you in this New Year!

References:

1. [1] http://www.medterms.com/script/main/art.asp?articlekey=6383.
2. [2] http://www.metapathogen.com
3. [3] The prion diseases Stanley B. Prusiner, Scientific American

-Pathogen Killer

If you haven’t used Olive Leaf Extract (OLE) before, you’ve been missing out on one of nature’s best botanicals to eradicate pathogens of various kinds.  Even though Olive Leaf Extract has been written about medically since 1854, it wasn’t until the Upjohn Corporation started looking into its potent virucidal possibility that Olive Leaf Extract came into its own and now is currently being used widely in the complementary and alternative medicine community. Its ability to act as a natural pathogen killer rivals very few other natural substances.  It kills pathogens such as viruses by inhibiting the replication process and interferes with the production of certain amino acids necessary to keep viruses alive. Olive Leaf Extract also kills bacteria by inactivating cellular enzymes critical for replication. That should be good news since flu season is right at the door. Ho, Ho, Ho!

Benefits

Olive Leaf Extract is commonly used to fight colds and flu, yeast infections, and viral infections such as the hard-to-treat Epstein-Barr disease, shingles and herpes. Olive Leaf Extract is also good for the heart and has shown to reduce low-density lipoproteins (LDL), or bad cholesterol and triglycerides. Researchers ^[1][2][3][4] have found that olive leaf extract lowers blood pressure and also increases blood flow by relaxing the side walls of coronary arteries and vessels.^[4]

Olive Leaf Extract also contains some of the best antioxidant properties known in nature. It helps protect the body from the continuous activity of free radicals.^{[2][5][6][7][8][9][10]} Free radicals are highly reactive chemical substances that, when oxidized, can cause cellular damage if left unchecked. Some recent research on the Olive Leaf Extract has shown its antioxidants to be effective in treating some tumors and cancers such as liver, prostate, and breast cancer, but the research on this is preliminary.^[11][12] Olive leaf can be especially potent when used in combination with other antioxidants or botanicals.

Olive Leaf Extract can be taken in several forms; liquid concentrate, dried leaf tea, powder, or capsule. However there are a few extracts that have more to them than most people are aware of.  For instance there is only one that contains a U.S. patent for Anti-Viral Therapy and it comes from Ameriden International, Inc. #6,117,844.  Many extracts are quickly gaining popularity due to their marketing, but few have the beneficial healing compounds found in The Original Olive Leaf Extract® (T.O.O.L.E.).

One of the most frequent comments heard from people after they start taking The Original Olive Leaf Extract® is that they feel more energetic and have a greater sense of well-being.

Side effects

Olive Leaf Extract can lower blood pressure and blood glucose. This may be an undesirable effect if the user already has low blood pressure and glucose levels. Sufferers of low blood pressure or low diabetes are particularly at risk. Users of Olive Leaf Extract need to drink enough water with their daily dosage or they may experience Herxheimers response otherwise known as “Die-Off” which may feel like flu symptoms. This may occur because the body is not able to rid the dead or dying pathogens fast enough, but the situation can be remedied usually by drinking more than enough water recommended which is usually 1 full glass (8oz or more) with each use.

Conclusion: Olive Leaf Extract is of great benefit due to its low potential for harm and great potential to stop what’s harming you, but a caution does exist: Always consult your Healthcare practitioner before you start or stop any medical regime. Interactions with pharmaceutical drugs which force the body to lower its blood pressure and glucose levels may occur in certain people and could be dangerous. Stop taking Olive Leaf Extract if you are going to use a synthetic antibiotic since there is a possibility of canceling each other out. Go slow at first using only the minimal amount suggested on the label and increase by one capsule until you see results.

If you’re looking for a good deal, Ameriden’s entire product line is ON SPECIAL during December including “The Original Olive Leaf Extract^®.”

For more information please contact AMERIDEN at 1-760-728-0747

References

• “Olive leaf extract exhibits antiviral activity against viral hemorrhagic septicemia rhabdovirus (VHSV)”
• [a]“Induction of Growth Inhibition and Differentiation of Human Leukemia HL-60 Cells by a Tunisian Gerboui Olive Leaf Extract”

• [b] “Olea europaea: A Phyto-Pharmacological Review

1. ^  Perrinjaquet-Moccetti et al. Food Supplementation with an Olive (Olea europaea L.) Leaf Extract Reduces Blood Pressure in Borderline Hypertensive Monozygotic Twins, 2008.
2. ^  Somova et al. Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves, 2003.
3. ^  Khayyal et al. Blood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME induced hypertension in rats, 2002.
4. ^ Zarzuelo et al. Vasodilator effect of olive leaf, 1991.
5. ^  Dr Stevenson, L,. et al. Oxygen Radical Absorbance Capacity (ORAC) Report on Olive Leaf Australia’s Olive Leaf Extracts, Southern Cross University, 2005.
6. ^ Benavente-Garcia et al. Antioxidant activity of phenolics extracted from Olea europaea L. leaves, 2000.
7. ^ Saija et al. In vitro evaluation of the antioxidant activity and biomembrane interaction of the plant phenols oleuropein and hydroxytyrosol, 1998.
8. ^ Briante et al. Olea europaea L. leaf extract and derivatives: antioxidant properties, 2002.
9. ^ Speroni et al. Oleuropein Evaluated In Vitro and In Vivo as an Antioxidant, 1998.
10. ^ Pinelli et al. Quali-quantitative analysis and antioxidant activity of different polyphenolic extracts from Olea europea L. leaves, 2000.
11. ^ Hamdi et al. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor, 2005.
12. ^ Dr Stevenson, L,. et al. In vitro Biological Activities of Pure Olive Leaf Extract & High Strength Olive Leaf Extract, 2006.
13. Additional references on Olive Leaf Extract and it’s benefits: http://www.ameriden.com/healthspot/the-truth-about-olive-leaf-extract/

by Richard L. Hall, 2010

“Calcium elenolate is not in Olive Leaf Extract!”

Olive Leaf Extract is one of the most amazing herbal extracts…but what a lot of confusion has come with it.

Have you ever heard any of the following statements?

• “We alone concentrate right-handed calcium elenolate.”
• “We invented the olive leaf extract.”
• “We discovered the secret the Upjohn Company missed.”
• “There is only one method to produce olive leaf extract that is truly therapeutic.”
• “Ours is patented.”
• “We concentrate the R-elenolic acid or manipulate the stereochemistry.”

If you have been researching olive leaf extracts you have probably heard several of these statements and have become extremely confused, especially since there are 30+ companies offering what they consider a good olive leaf extract.

I can almost hear you asking, “What ever happened to, ‘It works, backed by proof?’” The answer is MARKETING!

Companies have to sell their products and if they can convince you that theirs is the best, better or the only one, hopefully, you will buy it. But BEWARE; many things being said about olive leaf extract are not exactly true!

It is time to end the confusion and reap the truth. We will back it up with proof so you will know where to go and will not be confused any longer. I am going to explain, in layman terms, some complicated things, but bear with me–there is light at the end of the tunnel!

After reviewing the list of constituents that come out of an olive leaf extract and not finding Calcium elenolate in it, in 1995 I called Harold Renis, a virologist who used to work for The Upjohn Company. He wrote many of the articles that pertained to Calcium elenolate at the time of testing. He agreed that Calcium elenolate came from acid hydrolysis of elenolic acid. Where by they boiled elenolic acid with calcium carbonate to produce Calcium elenolate. This also concurs with the patent on Calcium elenolate filed in 1962 by Scientist, W. L. C. Veer. (t)

It finally made sense! It does not happen in the body. It was produced in a lab. So what is it that is working in olive leaf extract? To understand this we have to start with what is in a good olive leaf extract.

1. Olive leaf extract has 98 constituents that can be pulled out of the raw leaves. (a)(m)(See Exhibit: Handbook of Phytochemical constituents of GRAS herbs & other economic plants list By Dr. James A. Duke, Author in the back of this article). As you look over these constituents the first thing you will notice is that there is no Calcium elenolate or Elenolic acid on the chart, but what you do find is Oleuropein.
2. Oleuropein (pronounced O-lee-u-ro-peen) has stereochemistry; in fact, it has many stereo-centers making it diastereomeric. That renders many left and right hands. (f) And although Oleuropein is diastereomeric containing (+ & -) it is only (-) levorotatory in nature according to the Merck index on phytochemicals. (b) (c) Levorotatory means that the molecule, Oleuropein, rotates light to the left in a polarimeter.When Oleuropein is ingested, it breaks down into other compounds, one of which is elenolic acid. Elenolic acid also has stereochemistry and is both (+) & (-) in nature. (Elenolic acid has been found to be highly virucidal in lab tests.) (d)(e)(g) Dr. Rebecca Braslau, Associate Professor of Chemistry at UCSC in California was contacted to verify the information stated above.
3. Two enzymes in your blood do the job of breaking down Oleuropein naturally. The enzymes, esterase & beta-glucosidase, automatically break down Oleuropein in the blood stream to predominately (+) dextrorotatory elenolic acid, no other process is needed. (h)(f)(d)As mentioned before elenolic acid does have stereochemistry and the dextrorotatory molecule of elenolic acid does not blood serum protein bind, remaining virucidal. That is the secret of why it works.  This means that olive leaf extract will work in your body according to the percentage of Oleuropein that is in it, the higher percentage the better.
4. Dextrorotatory elenolic acid does not blood serum protein bind.
   In the late 70′s The Upjohn Company hydrolyzed (pulled out) elenolic acid from Oleuropein with mineral acid. (I) After mineral acid hydrolysis only the (-) levorotatory form of elenolic acid was produced. Then they took one of its hydrolysates, a salt of elenolic acid and combined it with calcium carbonate to produce calcium elenolate, which was also only (-) levorotatory, and tested it in the test tube and in humans. It worked great in the test tube (in vitro), but blood serum protein bound in all the human studies (in vivo) rendering it ineffectual. The dextrorotatory molecule however was never used.The difference? When Oleuropein is ingested, it quickly converts to elenolic acid and produces predominately-dextrorotatory elenolic acid. Bio-chemist W. L. C. Veer claimed that elenolic acid, in its dextrorotatory form, when ingested, produces a hypotensive effect in animal & human studies. W. V. Cruess discovered that esterase & beta-glucosidase enzymes were in the olive tree. It was further noted by Cruess that it is beta-glucosidase that hydrolyzes Oleuropein to the (+) dextrorotatory form of elenolic acid, which we now know, does not blood serum protein bind. William R. Fredrickson hypothesized that these same two enzymes would be present in your blood. W. R. Fredrickson also discovered that because of these two enzymes, Oleuropein would automatically change to predominately (+) dextrorotatory elenolic acid in the body. After talking with Harold Renis, he informed me that they (The Upjohn Co.) believed that the left-handed molecule (Levorotatory) was the virucidal form, so they disregarded the right-handed form. (j) Further investigation and independent studies have proved that William R. Fredrickson was correct, right-handed molecules of elenolic acid do not blood serum protein bind. (e)(d)(k)(t)
5. Calcium elenolate is not in olive leaf extracts nor does it occur in your body. When researching olive leaf extract components, calcium elenolate is never shown as a component. (a)  That is because calcium elenolate, being a hydrolysate (a salt) of elenolic acid, is a synthesized compound produced in the lab by mineral acid hydrolysis. You create calcium elenolate by boiling calcium carbonate with elenolic acid. (t)  This cannot happen in your body. The Upjohn Company, known for producing synthetics, knew that elenolic acid by itself exists as an oil (natural form) and first needed to be converted to a crystalline salt (synthetic) form in order for it to be used in their testing. The molecule of calcium elenolate is only one ion different than that of the molecule of elenolic acid. It is interesting to note that when calcium elenolate is ingested it readily converts back to elenolic acid when mixed with stomach acids. In today’s market calcium elenolate could be produced synthetically and then mixed with the natural extract, but that would be extremely expensive. (j)(l)(t) To date no scientific or medical literature exists to show that the body converts elenolic acid to calcium elenolate.
6. Calcium elenolate cannot be concentrated (+ or -) from an olive leaf extract. Since calcium elenolate does not appear in olive leaf extracts, (a) it is impossible to concentrate it. However there are some companies that would like you to believe they do. (n) Why? Again, Marketing! They’ve got to be different, right?
7. Oleuropein can be concentrated! Since it is Oleuropein in the olive leaf extract, not elenolic acid or calcium elenolate, Oleuropein is then what is concentrated from an extract. For every molecule of Oleuropein concentrated from olive leaf extract, when consumed, seven molecules of dextrorotatory elenolic acid & one molecule of levorotatory elenolic acid are produced. The more Oleuropein you concentrate the more elenolic acid you have. (e)(h)(p)
8. Who really discovered the solution to blood serum protein binding? One company claims that in 1995 they discovered the solution to the blood serum protein-binding problem that The Upjohn Company came up against in the 70′s. (n) But the truth is it was William Robert Fredrickson, a lay chemist that uncovered the mystery in 1989. (o) Fredrickson found that when Oleuropein entered the blood stream it was automatically changed predominately to dextrorotatory elenolic acid because of the two enzymes esterase & beta-glucosidase. William Fredrickson published his papers (which are in the Library of Congress) (h) (I have two (2) copies of his book) to this effect.   The vice president of the company, claiming to have solved the mystery, use to be William Fredrickson’s partner in 1993 (NFN Company) before he was vice president of the current company making the claim. (Where he received his information on how to make a good olive leaf extract is clear since William Fredrickson was the only chemist among them).
9. In 1995 there was only one company making an olive leaf extract and  only one company extracting OLE into a powder form in the United States using a method, which keeps the Oleuropein molecule alive. (s) It is true that all conventional methods of manufacture at that time would have produced an extract that would have been useless in the body. All conventional methods at that time were too hot and would burn up the Oleuropein molecule. (n) Oleuropein is classified as an iridoid by nature and iridoids can be extremely heat sensitive, including unstable. (r) Today, there are other methods that are producing good olive leaf extracts, which can be dried in to a powder form. Please keep in mind that liquid extracts have been around for 100’s of years. So when a company states, “We invented it” what they are really saying is that they came up with a method, not that they invented OLE.
10. Patents & patents pending. Currently there are at least 8 patents or patent pending either on a process, extract or attaching themselves to olive leaf extracts.  We hold the U. S. Patent #6,117,844 for Method for Antiviral Therapy and William Fredrickson’s U.S. Patent # 6,455,580 just pass recently claiming the effective use of elenolic acid.  It is a concern that the one company claiming they alone discovered the mystery to the blood serum protein-binding problem, who has patent protection for their proprietary extraction process, also claimed in earlier literature that the process concentrated right-reflecting calcium elenolate. (n) What’s amazing about this statement is that their United States Patent #5,714,150 does not say that!  It says, in its summary, “It is therefore an object of the invention to provide a method for extracting Oleuropein in a form which retains medicinal activity in vivo. It is a further object of the invention to provide Oleuropein in a form which undergoes hydrolysis in vivo to produce elenolic acid which retains its antiviral activity, and which does not bind to proteins in the blood.” (See anything about calcium elenolate there?) “Applicants believe the resultant Oleuropein contains a high proportion of R (right-handed) Oleuropein as compared with L (left-handed) Oleuropein.” They have since changed their story, claiming their process results in a concentration of right reflecting molecules of elenolic acid in the body. They also have changed the name of their extract throughout the years.  The fact is, their process is not unique and does not change the Oleuropein molecule, verified by biochemists.  Most Olive Leaf Extracts will yield elenolic acid in the body concentrated proportionately to the percentage of Oleuropein they started with.  Once again, the higher the percentage of Oleuropein you start, with the higher the concentration of elenolic acid you end up with. (t)(u)(v)There are those who might argue the point that concentrating Oleuropein diminishes all the other synergistic phytochemicals.  That is a possibility if a manufacture selectively extracts Oleuropein using just a simple extraction method.  However, there are several methods of extraction.  Olive Leaf extract usually has many coverings of alcohol and or water, which produce various amounts of phytochemicals each time it is covered depending on the solvent and temperature. Example: If a manufacture uses a non-selective extract method, with three or more coverings of alcohol, they will end up with a fairly predictable substance, but if the same extract was selective for just concentrating Oleuropein the end result would be very high in oleuropein, but very low in the other active phytochemicals. The same manufacture, if it were to use a non-selective extract method and after covering the extract three times, drain off the extract, continued to cover the balance and selectively pulled out additional Oleuropein and merge that with the first extract you end up with quite a different final product, higher in Oleuropein and a higher amount other the other active phytochemicals. The extract named “The Original Olive Leaf Extract” follows the manufacture and administration of U.S. Patent #6,117,844 Example 1-C, which produces a synergistic effect with the other natural flavonoid components of olive leaf, such as: the hydroxytyrosol group, oleoside group, cafferic acid, rutin, hesperidein and luteolin-7-glucoside. U. S. Patent #6,117,844, for Antiviral Therapy claims a method for treating warm-blooded vertebrates suffering from disease of viral origin and wherein the compound is Oleuropein to be orally administered to said vertebrate. A therapeutically effective amount of the antiviral composition is to comprise a compound selected from the group consisting of Oleuropein at a dose of 30mg to 500mg of Oleuropein.
11. Where is the original olive leaf extract? Since extracts have been made for hundreds of years, no one really knows! We do know however, that in 1811 Dr. Pallas used his own liquid extract to stop malaria fever out breaks on the island of Mytelene. France has also produced powdered olive leaf extracts for more than 50 years. The current company labeling their product “The Original Olive Leaf Extract” pertains to the brand name only and not that they invented olive leaf extract, others, sadly, are claiming to be the original and they are not! (w)(x)
12. Currently, there is no extract in the retail market today in a powder form that contains higher than 27% Oleuropein when tested by the Merck Index HPLC test procedure. Many companies claim very high percentages of Oleuropein however when tested fall drastically short of thier stated claims.
13. 13. A balanced (synergistic) extract of flavanoids & phytochemicals works much better than an extract with just high Oleuropein alone. (o)(q)
14. 14. All extracts are not manufactured the same way!Not everyone is privy to formulas that work really well. Consider Coca cola. Do you think there is a company that has their formula? Of course not, even though many have tried, like Pepsi etc. The same is true with the olive leaf extract. The formulation of extracts and their process can produce quite different results. There are some olive leaf extracts on the market that work really well and others that do not. And unfortunately there are some that are worthless. (y)

Here are some other note worthy facts about Olive Leaf Extracts; Oleuropein, when extracted from olive leaves, along with the other phytochemicals (a), works as a very wide spectrum natural antibiotic, (o) (q) but it does not work on all conditions for all people. There are people that this wonderful extract will not work on.  How can you tell you are one of those people? You can’t! You simply have to try it.

As good as Olive Leaf Extracts are, they should not be taken along with Antibiotics derived from molds or fungus and certain additional Amino Acid isolates. Antibiotics if they are derived from mold or fungus, when confronted with Oleuropein, may inhibit them or kill them, wasting the effectiveness of both.  It is not clear if the same is true with antibiotics not created from molds or fungus.

Amino Acids- one clinical study showed that when elenolic acid (produced from the conversion of Oleuropein) was introduced to equal amounts of either; lysine, glycine, cysteine or histidine it canceled equal part out (counteractive effect), wasting the effacacy of both.  Either of these experiences could be frustrating so try and avoid taking them together if possible.

Those using blood thinners should take extra care and seek advice from their health care provider before using Olive Leaf Extract. Olive Leaf Extract has a relaxing effect on the coronary walls of veins and arteries, which makes them more pliable and easier to burse.

Those on blood pressure medications should also seek advice from their health care provider before using olive leaf extract due to olive leaf extracts (hypertensive) blood pressure lowering effect.
Each issue can vary in relation to your body weight & metabolism. Many times people believe it doesn’t work for them simply because they are not taking enough  or are using a weak brand and sometimes Olive Leaf Extract just will not work on a particular issue for a particular person and no one knows why, but antidotal evidence has shown that most people will receive benefit for most common issue.

Die-off effect (Herxheimer reaction) to help avoid this effect drink plenty of water and if shortly after starting on olive leaf extract you experience cold or flu like symptoms decrease the dosage you take by one capsule each time you take them until the issues go away. I would recommend not stopping it all together if possible, as you will have to start your protocol all over. (k)

If you are concerned about the amount of Oleuropein your product has, call the company on the bottle and ask for a certificate of analysis of the batch number located on the container you’ve purchased.

If after reading this article you may want to do further research on the web.  We would suggest PubMed and Medline if you have an account. Also please feel free to visit us on the web at www.ameriden.com for more information.

GOOD NEWS!

The ORIGINAL OLIVE LEAF EXTRACT®, produced exclusively for AMERIDEN International, Inc., is a call away.

Each vegetarian friendly capsule (vegetable cellulose) contains 500mgs of OLE (US Patent # 6,117,844) with  standardized 20%  Oleuropein (HPLC Verified)
And 25mg of Naringin creating a unique delivery system in the body.
for a total of 525mg per capsule.

About the Author:

Richard L. Hall is an agriculturist & herbalist who have been involved with the process of olive leaf extract coming to market since its inception in 1989. His company harvested and provided the olive leaves for William R. Fredrickson, the original lay-chemist, who discovered and solved the problem of blood serum protein binding that The Upjohn Company had in the 70′s.  Mr. Hall’s company also provides “The Original Olive Leaf Extract” under the Trademarked name “OlivFactor” for Private Labeling” in the United States as well as internationally.  Because of the high cost of labor in the U. S., 99% of all leaf used for commercial production of Olive Leaf extract is harvested from either Spain, Greece, Italy, France, Israel and some in Mexico (one source).  “The Original Olive Leaf Extract” uses only leaf processed in Spain, as it is the highest quality.  The trees are not chemically sprayed or chemically fertilized and the leaves can be harvested year round. As CEO of AMERIDEN International, Mr. Hall and his staff are dedicated to the truth and providing proven Nutraceuticals, which are Bio-Active.

References

1. Handbook of phytochemical constituents of GRAS herbs & other economic plants. by James A. Duke, Author (U.S.D.A.)
2. The Merck Index, 10th edition, Oleuropein, Pg. 980
3. Dictionary of Organic Compounds, 5th Vol. 3, Oleuropein PP 4400-01
4. W. V. Cruess, Oleuropein, The bitter principal of the olive. IV Congress Intern. Tech. Chem. Ind. Agr. Brussels, 3:638-45, 1935
5. P. Gariboldi, et,al Secoiridoids from Olea europaea. Phyto-Chemistry 25(40):865-69 1986
6. Antimicrobial Properties of Oleuropein & Products of its hydrolysis from green olives. H. P. Fleming, W. M. Walters, Jr. & J. L. Etchells, Applied Microbiology, Nov 1973, Vol. 26 #5 PP 777-82.
7. Kaij-a-Kamb, M; Amoros, M; Girre, L. “Search for new antiviral agents of plant origin. Pharma-Acta-Helv, 67(5-6):130-47, 1992
8. The Tree of Life, William R. Fredrickson, Library of Congress, Pg 87, 1994
9. In Vitro Antiviral Activity of Calcium Elenolate Harold Renis, Dept. of Virology, Antimicrobal Agents & Chemotherapy PP 167-72, 1969
10. Elenolic Acid to Calcium Elenolate. Conversation with Harold Renis and Richard Hall Ameriden International and Harold Renis March, 1999
11. Olive Leaf Extract, Natures Antibiotic, Dr. Morton Walker, How olive leaf extract works against Microbes. Pg 42, 1997
12. Inactivation of DNA polymerase of Murine Leukemia Viruses by Calcium elenolate. Nature New Biology Vol. 238 Aug. 30, 1972
13. Antioxidative Activities of Olea europaea leaves & related compounds. Bernard Le Tutour & Didier Gueden, Phytochemistry Vol. 31, #4, PP1173-78, 1992
14. Olive Leaf Extract, Natures secret for Vibrant Health & Long Life. The National Life Extension Research Institute, Sixth Printing, Pg. 18, 1998
15. The Tree of Life, William R. Fredrickson, Library of Congress. PP 111-114, 1994
16. W. V. Creuss, C. L. Alsberg. The Bitter Glucoside of Olive. Journal of Amer. Chem. Soc. 56:2115-17, 1934
17. Olive Leaf Extract. Video- Doctor to Doctor Show, TBN
18. Pharmacological Analysis of the Iridiod Oleuropein V. Petkov & P. Manolov, Arzneim-Forsch (Drug Res.) 22(9) 1173-1178, Nov. 1992
19. Olive Leaf Extract, Nature’s Antibiotic, Dr. Morton Walker, Benefits of Taking Olive Leaf Extract Components. Pg. 44, 1997
20. W. L. C. Veer, U. S. Patent #3,033,877 1962. Also, Journal Rec. Trav. Chem. 76:839-40. 1957
21. Method & composition for Antiviral Therapy with Olive Leaves. Docket #6524-23686 William R. Fredrickson, 1994
22. Method for Producing Extract of Olive Leaves. Pat. #5,714,150  Feb.3, 1998, Les Nachman, Inventor
23. Provincial Transactions, The Febrifuge Properties of the Olive. D. Hanbury, Re: Dr. Pallas PP 353-354, 1854
24. Olive Leaf Extract, Nature’s Antibiotic. Dr. Morton Walker. Uncovering the Therapeutic Components of Olive Leaf Extract. Pg. 53, 1997
25. Pharmline Inc. Laboratory Tests Performed 7/98 Bio-chemist, Duane Dostie, Dr. Zakir Ramazanov

Other Sources

• Phyto-chemical constituents of GRAS herbs and other economic plants. James A. Duke, Author
• Olive Leaf Extract, Nature’s Secret for Vibrant Health & Long Life. Pg. 18, 1998
• U. S. Patent #5,714,150 Method for Producing Extract of Olive Leaves. Leslie Nachman, Inventor
• U.S. Patent #6,117,844 Method and composition for Antiviral Therapy. William R. Fredrickson, Inventor
• Dr. Dixon, Testimony of effectiveness of Ameriden’s “The Original Olive Leaf Extract” & others.
• HPLC results from Pharmline, Inc. showing claimed percentages of Oleuropein and their true percentages. Aug. 10th, 1998
• Dr. Rebecca Braslau, Associate Professor of Chemistry at UCSC California.1999

Additional Olive Leaf Extract References and Research

1. Moreno, J. A., J. Lopez-Miranda, et al. (2003). “[Effect of phenolic compounds of virgin olive oil on LDL oxidation resistance].” Med Clin (Barc) 120(4): 128-31.
2. Bisignano, G., A. Tomaino, R. Lo Cascio, G. Crisafi, N. Uccella and A. Saija (1999). “On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol.” J Pharm Pharmacol 51(8): 971-4.
3. Caruso, D., B. Berra, F. Giavarini, N. Cortesi, E. Fedeli and G. Galli (1999). “Effect of virgin olive oil phenolic compounds on in vitro oxidation of human low density lipoproteins.” Nutr Metab Cardiovasc Dis 9(3): 102-7.
4. Coni, E., R. Di Benedetto, M. Di Pasquale, R. Masella, D. Modesti, R. Mattei and E. A. Carlini (2000). “Protective effect of oleuropein, an olive oil biophenol, on low density lipoprotein oxidizability in rabbits.” Lipids 35(1): 45-54.
5. de la Puerta, R., E. Martinez-Dominguez and V. Ruiz-Gutierrez (2000). “Effect of minor components of virgin olive oil on topical anti-inflammatory assays [In Process Citation].” Z Naturforsch [C] 55(9-10): 814-9.
6. Esti, M., L. Cinquanta and E. La Notte (1998). “Phenolic Compounds in Different Olive Varieties.” J Agric Food Chem 46(1): 32-35.
7. Gonzalez, M., A. Zarzuelo, M. J. Gamez, M. P. Utrilla, J. Jimenez and I. Osuna (1992). “Hypoglycemic activity of olive leaf.” Planta Med 58(6): 513-5.
8. Onderoglu, S., S. Sozer, K. M. Erbil, R. Ortac and F. Lermioglu (1999). “The evaluation of long-term effects of cinnamon bark and olive leaf on toxicity induced by streptozotocin administration to rats.” J Pharm Pharmacol 51(11): 1305-12.
9. Perri, E., A. Raffaelli and G. Sindona (1999). “Quantitation of oleuropein in virgin olive oil by ionspray mass spectrometry-selected reaction monitoring.” J Agric Food Chem 47(10): 4156-60.
10. Petroni, A., M. Blasevich, M. Salami, N. Papini, G. F. Montedoro and C. Galli (1995). “Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil.” Thromb Res 78(2): 151-60.
11. Servili, M., M. Baldioli, R. Selvaggini, A. Macchioni and G. Montedoro (1999). “Phenolic compounds of olive fruit: one- and two-dimensional nuclear magnetic resonance characterization of Nuzhenide and its distribution in the constitutive parts of fruit.” J Agric Food Chem 47(1): 12-8.
12. Visioli, F., G. Bellomo and C. Galli (1998). “Free radical-scavenging properties of olive oil polyphenols.” Biochem Biophys Res Commun 247(1): 60-4.
13. Visioli, F., S. Bellosta and C. Galli (1998). “Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages.” Life Sci 62(6): 541-6.
14. Visioli, F. and C. Galli (1994). “Oleuropein protects low density lipoprotein from oxidation.” Life Sci 55(24): 1965-71.
15. Visioli, F. and C. Galli (2001). “Antiatherogenic Components of Olive Oil.” Curr Atheroscler Rep 3(1): 64-67.
16. Zarzuelo, A., J. Duarte, J. Jimenez, M. Gonzalez and M. P. Utrilla (1991). “Vasodilator effect of olive leaf.” Planta Med 57(5): 417-9.
17. Zarauelo A et al, Vasodilator effect of olive leaf, Planta Med., 1991; 57(5), 417-19.
18. Samuelsson G, The blood pressure lowering factor in leaves of Olea Europaea. Farmacevtisk Revy, 15:229-39.
19. Department of Pharmacology and Toxicology, Society of Pharmaceutical Industries of Tunis, Hypotension, hypoglycemia and    hypouricemia recorded after repeated administration of aqueous leaf extract of Olea europaea, Belgian Pharmacology Journal, March-April 1994; 49(2), 101-8.

Everyone has probably heard the word disease and can relate to it as some kind of plague of mankind, but what I believe people experience over time is ‘Dis-Ease’ with the whole situation of their health. Could it be if they just had a little peace with the process they would heal faster?

As I reflect over more than 40 years of trekking the long & winding road to great health, I cannot help, but realize my ‘assignment’ in life was to get healed; then to help others achieve the same status I have. The knowledge of maintaining or regenerating our health is right at our fingertips, so the question is “do I wait until I am sick or do I take action today.” I didn’t just go into the health care industry I grew into it! It began many years ago when I was a young, know-it-all 20 year old pursuing my dreams, studying philosophy, literature, & the humanities at a local city college while raising 2 daughters and working a 7 day shift in the restaurant business. You know, the normal everyday non-stressful life, yeah, right!

As with most, my symptoms of ‘Dis-Ease’ began in my teenage years when I wasn’t sick, but I was living in denial and I don’t mean the river in Egypt!

I began having blackouts, but was too afraid to tell anyone or do anything about them. That was most uncomfortable. I began seeing doctor after doctor and I took everything they instructed me to take and yet I did not improve; sound familiar? My disease was fast becoming my ‘Dis-Ease.’ I was “shocked” when a doctor told me I had to go to the hospital immediately because I was losing red blood cells.

Losing blood cells, where, I didn’t see or feel them leaving, where were they going, what was happening to me? The loss was from an ulcer big enough to cause such bad gastrointestinal problems that my respiratory system and skin soon gave way to allergies. The list grew quickly; what was happening to my youth? I was overwhelmed with fear, but I couldn’t give up, where would I find an answer to my problem? Weeks of testing and treatment for the bleeding ulcer ultimately cured it, but I was still at ‘Dis-Ease’ with the whole trauma.

Elated that it was gone, I was able to resume my life once again, but went right back to the cause of my ulcer, junk food. I didn’t know food played such a big deal in overall health.

Within 3 days of my junk food diet, the bleeding returned. Suddenly I came to the realization of why I had Dis-Ease, if I continued on the junk food highway, I might not live to see my 30th birthday! So began my journey to health and a ‘Dis-Ease’ Free life. It took me two more years, countless hours of soul searching & divine intervention until I was ready. Peace for some doesn’t come cheap!

I started taking Advanced Nutritional classes that were outside of the traditional realm. Can you imagine how unusual this was in the 70’s? My research & studies put me on a 360º turnaround and I have never looked back! Fortunately, for me this was a perfect time in history and my transition had great help from such mentors as Dr. Bernard Jenson, Dr. Paul Bragg, Dr. Carlton Fredericks & Dr. Benjamin Franks. I also had the privileged to have met & learned from Dr. Jonathan Wright, Dr. David Williams, Weston Price, Jack Challen, Dr. Robert Jay Rowen & Dr. Sherry Rogers to name a few. Few! That’s a whole lot of great advice.

Now let’s fast-forward 12 years, I was juicing daily, eating healthy & feeling fantastic when the dietary supplement market exploded. I knew I had to share what I learned with others so I started my own company “Vital Nutrients.” I promised myself years ago that when I started I would only work with companies who had integrity, credibility and manufactured a high quality product and I have kept my promise all along. As a result, my business continues to bring me great joy and wonderful clients who I am able to help with their health concerns.

Sometimes I feel like the “Natural Nutritional” version of Detective Colombo, but in this distinctive way, I am able to also connect with a unique variety of cliental. My clients are faithful because of my deep commitment to them and the high quality products I carry. Some of my favorites are “The Original Olive Leaf Extract” & “Rosavin Plus” by Ameriden International, Inc. It also helps that I personally use these products; I will continue to keep them as part of my daily regime and I know my clients do as well.

Our society may be caught up in the Big Pharma & the Alice in Wonderland paradigm of modern medicine, which has its place, but a healthy body & mind at peace brings homeostasis, there is nothing like it, may you all find it.

Sincerely Ron Pellegrini

Stone Mountain Center…… where Stephen Larsen PhD focuses his attention on neurofeedback and nutraceutical support to help patients restore their lives.

In 1990, after 28 years of teaching biofeedback and self-regulation techniques to college students (at SUNY Ulster), Dr. Stephen Larsen set up his own healing and counseling center at Stone Mountain Farm on a piece of choice Hudson Valley landscape, with forests, rock-climbing cliffs, and waterfalls. His wife Robin was already running a not-for profit center there, The Center for Symbolic Studies, which included seminars in personal growth, traditional wisdom, and sports challenges such as rock climbing and the flying trapeze.

Read the rest of this article »

Laurel Dewey – Author

As a professional author, I understand stress. I know what a looming deadline feels like in the gut. I comprehend what an all-night re-write does to the brain. I really get what waiting for the reviews can do to my adrenal glands. While I wouldn’t choose any other profession, I’m patently aware that my chosen occupation requires a certain amount of physical support that’s beyond a brisk walk to clear the head. As I get older, I’m reminded repeatedly how without that support, I’d be operating way below par.

Twenty years ago when I got my first “real” writing job in Los Angeles, I knew nothing about herbs called “adaptogens.” I wish I had known because I probably wouldn’t have burnt out so quickly Read the rest of this article »

Dr. Abram Ber

Born 68 years ago in Rumania to Jewish parents, by God’s grace, his immediate family was able to escape the horrors of the war by moving first to Italy, and finally settling in Montreal, Canada. Grace and perhaps a little luck brought him to Scottsdale, Arizona, where he has practiced homeopathic medicine for 30 years.

Abram Ber earned his medical degree from McGill University, with a specialty in anesthesiology. His training included the Royal College of Physicians and Surgeons of Canada, Royal Victorian Hospital (resident staff of anesthesiology). It was during this period in his life that he connected the dots between nutrition, diseases, and healing. His quest for knowledge brought him to Arizona in the late 1970s, where he has been in private practice ever since. Read the rest of this article »