Ameriden HealthSpot

The Truth About Olive Leaf Extract

admin — Tue, 15 Jun 2010 00:31:55 +0000

by Richard L. Hall, 2010

“Calcium elenolate is not in Olive Leaf Extract!”

Olive Leaf Extract is one of the most amazing herbal extracts…but what a lot of confusion has come with it.

Have you ever heard any of the following statements?

“We alone concentrate right-handed calcium elenolate.”
“We invented the olive leaf extract.”
“We discovered the secret the Upjohn Company missed.”
“There is only one method to produce olive leaf extract that is truly therapeutic.”
“Ours is patented.”
“We concentrate the R-elenolic acid or manipulate the stereochemistry.”

If you have been researching olive leaf extracts you have probably heard several of these statements and have become extremely confused, especially since there are 30+ companies offering what they consider a good olive leaf extract.

I can almost hear you asking, “What ever happened to, ‘It works, backed by proof?’” The answer is MARKETING!

Companies have to sell their products and if they can convince you that theirs is the best, better or the only one, hopefully, you will buy it. But BEWARE; many things being said about olive leaf extract are not exactly true!

It is time to end the confusion and reap the truth. We will back it up with proof so you will know where to go and will not be confused any longer. I am going to explain, in layman terms, some complicated things, but bear with me–there is light at the end of the tunnel!

After reviewing the list of constituents that come out of an olive leaf extract and not finding Calcium elenolate in it, in 1995 I called Harold Renis, a virologist who used to work for The Upjohn Company. He wrote many of the articles that pertained to Calcium elenolate at the time of testing. He agreed that Calcium elenolate came from acid hydrolysis of elenolic acid. Where by they boiled elenolic acid with calcium carbonate to produce Calcium elenolate. This also concurs with the patent on Calcium elenolate filed in 1962 by Scientist, W. L. C. Veer. (t)

It finally made sense! It does not happen in the body. It was produced in a lab. So what is it that is working in olive leaf extract? To understand this we have to start with what is in a good olive leaf extract.

Olive leaf extract has 98 constituents that can be pulled out of the raw leaves. (a)(m)(See Exhibit: Handbook of Phytochemical constituents of GRAS herbs & other economic plants list By Dr. James A. Duke, Author in the back of this article). As you look over these constituents the first thing you will notice is that there is no Calcium elenolate or Elenolic acid on the chart, but what you do find is Oleuropein.
Oleuropein (pronounced O-lee-u-ro-peen) has stereochemistry; in fact, it has many stereo-centers making it diastereomeric. That renders many left and right hands. (f) And although Oleuropein is diastereomeric containing (+ & -) it is only (-) levorotatory in nature according to the Merck index on phytochemicals. (b) (c) Levorotatory means that the molecule, Oleuropein, rotates light to the left in a polarimeter.When Oleuropein is ingested, it breaks down into other compounds, one of which is elenolic acid. Elenolic acid also has stereochemistry and is both (+) & (-) in nature. (Elenolic acid has been found to be highly virucidal in lab tests.) (d)(e)(g) Dr. Rebecca Braslau, Associate Professor of Chemistry at UCSC in California was contacted to verify the information stated above.
Two enzymes in your blood do the job of breaking down Oleuropein naturally. The enzymes, esterase & beta-glucosidase, automatically break down Oleuropein in the blood stream to predominately (+) dextrorotatory elenolic acid, no other process is needed. (h)(f)(d)As mentioned before elenolic acid does have stereochemistry and the dextrorotatory molecule of elenolic acid does not blood serum protein bind, remaining virucidal. That is the secret of why it works. This means that olive leaf extract will work in your body according to the percentage of Oleuropein that is in it, the higher percentage the better.
Dextrorotatory elenolic acid does not blood serum protein bind.
In the late 70′s The Upjohn Company hydrolyzed (pulled out) elenolic acid from Oleuropein with mineral acid. (I) After mineral acid hydrolysis only the (-) levorotatory form of elenolic acid was produced. Then they took one of its hydrolysates, a salt of elenolic acid and combined it with calcium carbonate to produce calcium elenolate, which was also only (-) levorotatory, and tested it in the test tube and in humans. It worked great in the test tube (in vitro), but blood serum protein bound in all the human studies (in vivo) rendering it ineffectual. The dextrorotatory molecule however was never used.The difference? When Oleuropein is ingested, it quickly converts to elenolic acid and produces predominately-dextrorotatory elenolic acid. Bio-chemist W. L. C. Veer claimed that elenolic acid, in its dextrorotatory form, when ingested, produces a hypotensive effect in animal & human studies. W. V. Cruess discovered that esterase & beta-glucosidase enzymes were in the olive tree. It was further noted by Cruess that it is beta-glucosidase that hydrolyzes Oleuropein to the (+) dextrorotatory form of elenolic acid, which we now know, does not blood serum protein bind. William R. Fredrickson hypothesized that these same two enzymes would be present in your blood. W. R. Fredrickson also discovered that because of these two enzymes, Oleuropein would automatically change to predominately (+) dextrorotatory elenolic acid in the body. After talking with Harold Renis, he informed me that they (The Upjohn Co.) believed that the left-handed molecule (Levorotatory) was the virucidal form, so they disregarded the right-handed form. (j) Further investigation and independent studies have proved that William R. Fredrickson was correct, right-handed molecules of elenolic acid do not blood serum protein bind. (e)(d)(k)(t)
Calcium elenolate is not in olive leaf extracts nor does it occur in your body. When researching olive leaf extract components, calcium elenolate is never shown as a component. (a) That is because calcium elenolate, being a hydrolysate (a salt) of elenolic acid, is a synthesized compound produced in the lab by mineral acid hydrolysis. You create calcium elenolate by boiling calcium carbonate with elenolic acid. (t) This cannot happen in your body. The Upjohn Company, known for producing synthetics, knew that elenolic acid by itself exists as an oil (natural form) and first needed to be converted to a crystalline salt (synthetic) form in order for it to be used in their testing. The molecule of calcium elenolate is only one ion different than that of the molecule of elenolic acid. It is interesting to note that when calcium elenolate is ingested it readily converts back to elenolic acid when mixed with stomach acids. In today’s market calcium elenolate could be produced synthetically and then mixed with the natural extract, but that would be extremely expensive. (j)(l)(t) To date no scientific or medical literature exists to show that the body converts elenolic acid to calcium elenolate.
Calcium elenolate cannot be concentrated (+ or -) from an olive leaf extract. Since calcium elenolate does not appear in olive leaf extracts, (a) it is impossible to concentrate it. However there are some companies that would like you to believe they do. (n) Why? Again, Marketing! They’ve got to be different, right?
Oleuropein can be concentrated! Since it is Oleuropein in the olive leaf extract, not elenolic acid or calcium elenolate, Oleuropein is then what is concentrated from an extract. For every molecule of Oleuropein concentrated from olive leaf extract, when consumed, seven molecules of dextrorotatory elenolic acid & one molecule of levorotatory elenolic acid are produced. The more Oleuropein you concentrate the more elenolic acid you have. (e)(h)(p)
Who really discovered the solution to blood serum protein binding? One company claims that in 1995 they discovered the solution to the blood serum protein-binding problem that The Upjohn Company came up against in the 70′s. (n) But the truth is it was William Robert Fredrickson, a lay chemist that uncovered the mystery in 1989. (o) Fredrickson found that when Oleuropein entered the blood stream it was automatically changed predominately to dextrorotatory elenolic acid because of the two enzymes esterase & beta-glucosidase. William Fredrickson published his papers (which are in the Library of Congress) (h) (I have two (2) copies of his book) to this effect. The vice president of the company, claiming to have solved the mystery, use to be William Fredrickson’s partner in 1993 (NFN Company) before he was vice president of the current company making the claim. (Where he received his information on how to make a good olive leaf extract is clear since William Fredrickson was the only chemist among them).
In 1995 there was only one company making an olive leaf extract and only one company extracting OLE into a powder form in the United States using a method, which keeps the Oleuropein molecule alive. (s) It is true that all conventional methods of manufacture at that time would have produced an extract that would have been useless in the body. All conventional methods at that time were too hot and would burn up the Oleuropein molecule. (n) Oleuropein is classified as an iridoid by nature and iridoids can be extremely heat sensitive, including unstable. (r) Today, there are other methods that are producing good olive leaf extracts, which can be dried in to a powder form. Please keep in mind that liquid extracts have been around for 100’s of years. So when a company states, “We invented it” what they are really saying is that they came up with a method, not that they invented OLE.
Patents & patents pending. Currently there are at least 8 patents or patent pending either on a process, extract or attaching themselves to olive leaf extracts. We hold the U. S. Patent #6,117,844 for Method for Antiviral Therapy and William Fredrickson’s U.S. Patent # 6,455,580 just pass recently claiming the effective use of elenolic acid. It is a concern that the one company claiming they alone discovered the mystery to the blood serum protein-binding problem, who has patent protection for their proprietary extraction process, also claimed in earlier literature that the process concentrated right-reflecting calcium elenolate. (n) What’s amazing about this statement is that their United States Patent #5,714,150 does not say that! It says, in its summary, “It is therefore an object of the invention to provide a method for extracting Oleuropein in a form which retains medicinal activity in vivo. It is a further object of the invention to provide Oleuropein in a form which undergoes hydrolysis in vivo to produce elenolic acid which retains its antiviral activity, and which does not bind to proteins in the blood.” (See anything about calcium elenolate there?) “Applicants believe the resultant Oleuropein contains a high proportion of R (right-handed) Oleuropein as compared with L (left-handed) Oleuropein.” They have since changed their story, claiming their process results in a concentration of right reflecting molecules of elenolic acid in the body. They also have changed the name of their extract throughout the years. The fact is, their process is not unique and does not change the Oleuropein molecule, verified by biochemists. Most Olive Leaf Extracts will yield elenolic acid in the body concentrated proportionately to the percentage of Oleuropein they started with. Once again, the higher the percentage of Oleuropein you start, with the higher the concentration of elenolic acid you end up with. (t)(u)(v)There are those who might argue the point that concentrating Oleuropein diminishes all the other synergistic phytochemicals. That is a possibility if a manufacture selectively extracts Oleuropein using just a simple extraction method. However, there are several methods of extraction. Olive Leaf extract usually has many coverings of alcohol and or water, which produce various amounts of phytochemicals each time it is covered depending on the solvent and temperature. Example: If a manufacture uses a non-selective extract method, with three or more coverings of alcohol, they will end up with a fairly predictable substance, but if the same extract was selective for just concentrating Oleuropein the end result would be very high in oleuropein, but very low in the other active phytochemicals. The same manufacture, if it were to use a non-selective extract method and after covering the extract three times, drain off the extract, continued to cover the balance and selectively pulled out additional Oleuropein and merge that with the first extract you end up with quite a different final product, higher in Oleuropein and a higher amount other the other active phytochemicals. The extract named “The Original Olive Leaf Extract” follows the manufacture and administration of U.S. Patent #6,117,844 Example 1-C, which produces a synergistic effect with the other natural flavonoid components of olive leaf, such as: the hydroxytyrosol group, oleoside group, cafferic acid, rutin, hesperidein and luteolin-7-glucoside. U. S. Patent #6,117,844, for Antiviral Therapy claims a method for treating warm-blooded vertebrates suffering from disease of viral origin and wherein the compound is Oleuropein to be orally administered to said vertebrate. A therapeutically effective amount of the antiviral composition is to comprise a compound selected from the group consisting of Oleuropein at a dose of 30mg to 500mg of Oleuropein.
Where is the original olive leaf extract? Since extracts have been made for hundreds of years, no one really knows! We do know however, that in 1811 Dr. Pallas used his own liquid extract to stop malaria fever out breaks on the island of Mytelene. France has also produced powdered olive leaf extracts for more than 50 years. The current company labeling their product “The Original Olive Leaf Extract” pertains to the brand name only and not that they invented olive leaf extract, others, sadly, are claiming to be the original and they are not! (w)(x)
Currently, there is no extract in the retail market today in a powder form that contains higher than 27% Oleuropein when tested by the Merck Index HPLC test procedure. Many companies claim very high percentages of Oleuropein however when tested fall drastically short of thier stated claims.
13. A balanced (synergistic) extract of flavanoids & phytochemicals works much better than an extract with just high Oleuropein alone. (o)(q)
14. All extracts are not manufactured the same way!Not everyone is privy to formulas that work really well. Consider Coca cola. Do you think there is a company that has their formula? Of course not, even though many have tried, like Pepsi etc. The same is true with the olive leaf extract. The formulation of extracts and their process can produce quite different results. There are some olive leaf extracts on the market that work really well and others that do not. And unfortunately there are some that are worthless. (y)

Here are some other note worthy facts about Olive Leaf Extracts; Oleuropein, when extracted from olive leaves, along with the other phytochemicals (a), works as a very wide spectrum natural antibiotic, (o) (q) but it does not work on all conditions for all people. There are people that this wonderful extract will not work on. How can you tell you are one of those people? You can’t! You simply have to try it.

As good as Olive Leaf Extracts are, they should not be taken along with Antibiotics derived from molds or fungus and certain additional Amino Acid isolates. Antibiotics if they are derived from mold or fungus, when confronted with Oleuropein, may inhibit them or kill them, wasting the effectiveness of both. It is not clear if the same is true with antibiotics not created from molds or fungus.

Amino Acids- one clinical study showed that when elenolic acid (produced from the conversion of Oleuropein) was introduced to equal amounts of either; lysine, glycine, cysteine or histidine it canceled equal part out (counteractive effect), wasting the effacacy of both. Either of these experiences could be frustrating so try and avoid taking them together if possible.

Those using blood thinners should take extra care and seek advice from their health care provider before using Olive Leaf Extract. Olive Leaf Extract has a relaxing effect on the coronary walls of veins and arteries, which makes them more pliable and easier to burse.

Those on blood pressure medications should also seek advice from their health care provider before using olive leaf extract due to olive leaf extracts (hypertensive) blood pressure lowering effect.
Each issue can vary in relation to your body weight & metabolism. Many times people believe it doesn’t work for them simply because they are not taking enough or are using a weak brand and sometimes Olive Leaf Extract just will not work on a particular issue for a particular person and no one knows why, but antidotal evidence has shown that most people will receive benefit for most common issue.

Die-off effect (Herxheimer reaction) to help avoid this effect drink plenty of water and if shortly after starting on olive leaf extract you experience cold or flu like symptoms decrease the dosage you take by one capsule each time you take them until the issues go away. I would recommend not stopping it all together if possible, as you will have to start your protocol all over. (k)

If you are concerned about the amount of Oleuropein your product has, call the company on the bottle and ask for a certificate of analysis of the batch number located on the container you’ve purchased.

If after reading this article you may want to do further research on the web. We would suggest PubMed and Medline if you have an account. Also please feel free to visit us on the web at www.ameriden.com for more information.

GOOD NEWS!

The ORIGINAL OLIVE LEAF EXTRACT®, produced exclusively for AMERIDEN International, Inc., is a call away.

Each vegetarian friendly capsule (vegetable cellulose) contains 500mgs of OLE (US Patent # 6,117,844) with standardized 20% Oleuropein (HPLC Verified)
And 25mg of Naringin creating a unique delivery system in the body.
for a total of 525mg per capsule.

About the Author:

Richard L. Hall is an agriculturist & herbalist who have been involved with the process of olive leaf extract coming to market since its inception in 1989. His company harvested and provided the olive leaves for William R. Fredrickson, the original lay-chemist, who discovered and solved the problem of blood serum protein binding that The Upjohn Company had in the 70′s. Mr. Hall’s company also provides “The Original Olive Leaf Extract” under the Trademarked name “OlivFactor” for Private Labeling” in the United States as well as internationally. Because of the high cost of labor in the U. S., 99% of all leaf used for commercial production of Olive Leaf extract is harvested from either Spain, Greece, Italy, France, Israel and some in Mexico (one source). “The Original Olive Leaf Extract” uses only leaf processed in Spain, as it is the highest quality. The trees are not chemically sprayed or chemically fertilized and the leaves can be harvested year round. As CEO of AMERIDEN International, Mr. Hall and his staff are dedicated to the truth and providing proven Nutraceuticals, which are Bio-Active.

References

Handbook of phytochemical constituents of GRAS herbs & other economic plants. by James A. Duke, Author (U.S.D.A.)
The Merck Index, 10th edition, Oleuropein, Pg. 980
Dictionary of Organic Compounds, 5th Vol. 3, Oleuropein PP 4400-01
W. V. Cruess, Oleuropein, The bitter principal of the olive. IV Congress Intern. Tech. Chem. Ind. Agr. Brussels, 3:638-45, 1935
P. Gariboldi, et,al Secoiridoids from Olea europaea. Phyto-Chemistry 25(40):865-69 1986
Antimicrobial Properties of Oleuropein & Products of its hydrolysis from green olives. H. P. Fleming, W. M. Walters, Jr. & J. L. Etchells, Applied Microbiology, Nov 1973, Vol. 26 #5 PP 777-82.
Kaij-a-Kamb, M; Amoros, M; Girre, L. “Search for new antiviral agents of plant origin. Pharma-Acta-Helv, 67(5-6):130-47, 1992
The Tree of Life, William R. Fredrickson, Library of Congress, Pg 87, 1994
In Vitro Antiviral Activity of Calcium Elenolate Harold Renis, Dept. of Virology, Antimicrobal Agents & Chemotherapy PP 167-72, 1969
Elenolic Acid to Calcium Elenolate. Conversation with Harold Renis and Richard Hall Ameriden International and Harold Renis March, 1999
Olive Leaf Extract, Natures Antibiotic, Dr. Morton Walker, How olive leaf extract works against Microbes. Pg 42, 1997
Inactivation of DNA polymerase of Murine Leukemia Viruses by Calcium elenolate. Nature New Biology Vol. 238 Aug. 30, 1972
Antioxidative Activities of Olea europaea leaves & related compounds. Bernard Le Tutour & Didier Gueden, Phytochemistry Vol. 31, #4, PP1173-78, 1992
Olive Leaf Extract, Natures secret for Vibrant Health & Long Life. The National Life Extension Research Institute, Sixth Printing, Pg. 18, 1998
The Tree of Life, William R. Fredrickson, Library of Congress. PP 111-114, 1994
W. V. Creuss, C. L. Alsberg. The Bitter Glucoside of Olive. Journal of Amer. Chem. Soc. 56:2115-17, 1934
Olive Leaf Extract. Video- Doctor to Doctor Show, TBN
Pharmacological Analysis of the Iridiod Oleuropein V. Petkov & P. Manolov, Arzneim-Forsch (Drug Res.) 22(9) 1173-1178, Nov. 1992
Olive Leaf Extract, Nature’s Antibiotic, Dr. Morton Walker, Benefits of Taking Olive Leaf Extract Components. Pg. 44, 1997
W. L. C. Veer, U. S. Patent #3,033,877 1962. Also, Journal Rec. Trav. Chem. 76:839-40. 1957
Method & composition for Antiviral Therapy with Olive Leaves. Docket #6524-23686 William R. Fredrickson, 1994
Method for Producing Extract of Olive Leaves. Pat. #5,714,150 Feb.3, 1998, Les Nachman, Inventor
Provincial Transactions, The Febrifuge Properties of the Olive. D. Hanbury, Re: Dr. Pallas PP 353-354, 1854
Olive Leaf Extract, Nature’s Antibiotic. Dr. Morton Walker. Uncovering the Therapeutic Components of Olive Leaf Extract. Pg. 53, 1997
Pharmline Inc. Laboratory Tests Performed 7/98 Bio-chemist, Duane Dostie, Dr. Zakir Ramazanov

Other Sources

Phyto-chemical constituents of GRAS herbs and other economic plants. James A. Duke, Author
Olive Leaf Extract, Nature’s Secret for Vibrant Health & Long Life. Pg. 18, 1998
U. S. Patent #5,714,150 Method for Producing Extract of Olive Leaves. Leslie Nachman, Inventor
U.S. Patent #6,117,844 Method and composition for Antiviral Therapy. William R. Fredrickson, Inventor
Dr. Dixon, Testimony of effectiveness of Ameriden’s “The Original Olive Leaf Extract” & others.
HPLC results from Pharmline, Inc. showing claimed percentages of Oleuropein and their true percentages. Aug. 10th, 1998
Dr. Rebecca Braslau, Associate Professor of Chemistry at UCSC California.1999

Additional Olive Leaf Extract References and Research

Moreno, J. A., J. Lopez-Miranda, et al. (2003). “[Effect of phenolic compounds of virgin olive oil on LDL oxidation resistance].” Med Clin (Barc) 120(4): 128-31.
Bisignano, G., A. Tomaino, R. Lo Cascio, G. Crisafi, N. Uccella and A. Saija (1999). “On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol.” J Pharm Pharmacol 51(8): 971-4.
Caruso, D., B. Berra, F. Giavarini, N. Cortesi, E. Fedeli and G. Galli (1999). “Effect of virgin olive oil phenolic compounds on in vitro oxidation of human low density lipoproteins.” Nutr Metab Cardiovasc Dis 9(3): 102-7.
Coni, E., R. Di Benedetto, M. Di Pasquale, R. Masella, D. Modesti, R. Mattei and E. A. Carlini (2000). “Protective effect of oleuropein, an olive oil biophenol, on low density lipoprotein oxidizability in rabbits.” Lipids 35(1): 45-54.
de la Puerta, R., E. Martinez-Dominguez and V. Ruiz-Gutierrez (2000). “Effect of minor components of virgin olive oil on topical anti-inflammatory assays [In Process Citation].” Z Naturforsch [C] 55(9-10): 814-9.
Esti, M., L. Cinquanta and E. La Notte (1998). “Phenolic Compounds in Different Olive Varieties.” J Agric Food Chem 46(1): 32-35.
Gonzalez, M., A. Zarzuelo, M. J. Gamez, M. P. Utrilla, J. Jimenez and I. Osuna (1992). “Hypoglycemic activity of olive leaf.” Planta Med 58(6): 513-5.
Onderoglu, S., S. Sozer, K. M. Erbil, R. Ortac and F. Lermioglu (1999). “The evaluation of long-term effects of cinnamon bark and olive leaf on toxicity induced by streptozotocin administration to rats.” J Pharm Pharmacol 51(11): 1305-12.
Perri, E., A. Raffaelli and G. Sindona (1999). “Quantitation of oleuropein in virgin olive oil by ionspray mass spectrometry-selected reaction monitoring.” J Agric Food Chem 47(10): 4156-60.
Petroni, A., M. Blasevich, M. Salami, N. Papini, G. F. Montedoro and C. Galli (1995). “Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil.” Thromb Res 78(2): 151-60.
Servili, M., M. Baldioli, R. Selvaggini, A. Macchioni and G. Montedoro (1999). “Phenolic compounds of olive fruit: one- and two-dimensional nuclear magnetic resonance characterization of Nuzhenide and its distribution in the constitutive parts of fruit.” J Agric Food Chem 47(1): 12-8.
Visioli, F., G. Bellomo and C. Galli (1998). “Free radical-scavenging properties of olive oil polyphenols.” Biochem Biophys Res Commun 247(1): 60-4.
Visioli, F., S. Bellosta and C. Galli (1998). “Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages.” Life Sci 62(6): 541-6.
Visioli, F. and C. Galli (1994). “Oleuropein protects low density lipoprotein from oxidation.” Life Sci 55(24): 1965-71.
Visioli, F. and C. Galli (2001). “Antiatherogenic Components of Olive Oil.” Curr Atheroscler Rep 3(1): 64-67.
Zarzuelo, A., J. Duarte, J. Jimenez, M. Gonzalez and M. P. Utrilla (1991). “Vasodilator effect of olive leaf.” Planta Med 57(5): 417-9.
Zarauelo A et al, Vasodilator effect of olive leaf, Planta Med., 1991; 57(5), 417-19.
Samuelsson G, The blood pressure lowering factor in leaves of Olea Europaea. Farmacevtisk Revy, 15:229-39.
Department of Pharmacology and Toxicology, Society of Pharmaceutical Industries of Tunis, Hypotension, hypoglycemia and hypouricemia recorded after repeated administration of aqueous leaf extract of Olea europaea, Belgian Pharmacology Journal, March-April 1994; 49(2), 101-8.

How Fresh Are Your Dietary Supplements?

admin — Sat, 01 May 2010 21:03:43 +0000

Expiration dates vs. Manufacture dates affects price and freshness

This coming June, all manufactures of dietary supplements must have in place the FDA’s updated compliancy regulations called cGMP’s. What does this mean to you, the consumer? Within these lengthy new regulations come several confusing surprises. One of these new surprises is the use of Manufacture date verses Expiration date. You will see either an Expiration Date or Manufacture Date on your supplements. Since the FDA published their Final Rule on 21CFR Part 111 in 2007 for current good manufacturing practices (cGMP’s) they have given manufactures the option of using either an Expiration Date or a Manufacture Date on their finished products.

The FDA declined to add a requirement for expiration /shelf-life dating, although the agency encourages its use. It seems the FDA believes there are not generally available methods for all ingredients sufficient to determine expiration dating, especially for botanical dietary ingredients. Manufacturers that do use an expiration date must now have scientific data/studies to support the selection of this date. If they do not have the supporting data the FDA could, at their discretion, impose fines, sanctions, recalls or closures on the company who manufactures the product.

Expiration and manufacture dates: What’s one to think?

The FDA guidelines do not include methodology or suggested procedures for the supporting data/studies; instead, they suggest “This is an evolving model.” What this means is that additional extensive stability studies must be undertaken that can last sometimes well over 6 months and will eventually increase costs sharply that will be passed on to the consumer. Most manufacturers are already burdened with the task of keeping the costs of products down on a regular basis.

But as far as FDA Regulations are concerned, any company who chooses to use expiration dates on their products must conduct these additional stability studies and provide the scientific data /studies to them before the product can be released to the market place.

With respect to Stability Testing of Dietary supplements & Nutraceutical Formulations, –From the FDA’s preamble text:

No requirements for dissolution, disintegration, bioavailability, or expiration dating occur because “scientific studies are still evolving…”
The agency considered whether to propose requirements in this proposed rule for expiration dating, shelf life dating, or best if used by dating, but is uncertain whether there are current and generally available methods to determine the expiration dating especially botanical dietary ingredients. We are not proposing expiration dating at this time because we have insufficient scientific information to determine the biological activity of certain dietary ingredients. . . Further, because official validated testing methods (i.e., AOAC or FDA) for dietary supplements are evolving, especially for botanical dietary ingredients, few official methods are available to asses the strength of a dietary ingredient in a dietary supplement

While all this information could be confusing for some, there is a light at the end of the tunnel with respect to Manufacture Date verses Expiration Date. Here are some Pros & Cons of this Proposed Rule:

CON:

When a product is bottled & labeled for distribution if the manufacture chooses to use the “Expiration Date,” additional holding time for stability studies must be added on before it can be sold at the consumer level. The finished product is then about 6-12 months old before it is even released for sale to you the consumer reducing freshness and overall efficacy, the very thing you want in your health products has now been decreased.

PRO:

The consumer may not be aware that most ‘Raw’ product manufacturers perform stability studies. They must hold & test their products usually somewhere between 1 and 6 months before they ship the “raw” unfinished goods to the manufacture.

While the FDA is caught in a quagmire of undetermined testing and validity, freshness and reliability is available via Manufacture dating. With Manufacture dating the finished product is ready to be sold at the consumer level without the extra-added 6-month wait. As a result, the product you purchase will not be decreased in freshness or efficacy.

We at AMERIDEN® have chosen to use the “Manufacture Date” on our finished products instead of the Expiration Date, as of February 2010, so you will receive the freshest product available when you order and will not incur an increased product cost that Expiration Dating would cause.

AMERIDEN® guarantees their products to be good for 3 years past the Manufacture Date.

Adaptogens & Medicine

admin — Thu, 01 Apr 2010 16:37:26 +0000

What are Adaptogens? Adaptogens help the body and brain cells “adapt” to and resist physical, chemical and environmental stress. They also help the body by normalizing the immune system and glucocorticoid hormone levels in a positive way, bringing them into balance.

Rhodiola rosea in late bloom

Rhodiola rosea is such an adaptogen with a common name called “Golden Root”, ever heard of it? It has more than 45 years of clinical studies and used in natural medicine for thousands of years.

How could something so good and with such a history of helping the body to adapt to and resist physical, chemical and environmental stress evade the medical community of the US? Five reasons:

There are 20 species of Adaptogens; most are unknown in the US market because they exist outside of the US.
Rhodiola rosea was kept as a “Soviet Secret” until after the Soviet Union collapsed. For those living in the Altai mountain range of Siberia, Rhodiola rosea has always been known as a natural medicine to help the body and brain cells “adapt”.
Since it is natural, US drug companies are not interested in something they cannot patent.
Alternative companies here in the US are not compelled by the FDA to run clinical trials nor do most have the money to invest in them.
It was not standardized until recent years. However, with that said here are reasons why you might want to investigate this compound.

Most drugs do not have 20 years of clinical studies, Rhodiola rosea has 45 years of documented clinical studies in Europe and in practice by professionals in the US for more that 12 years. Most drugs have multiple unwanted side-effects and cannot be taken with other drugs. Rhodiola rosea only has a couple minor side effects, heightened dreams and agitations at high amounts. Many professionals are claiming side benefits rather than side effects and rhodiola rosea can be taken with most drugs. It’s safe and inexpensive. The only draw back might be that health plans do not cover it, but then most health plans today have co-pays exceeding the cost of purchasing Rhodiola rosea on line. You need a brand you can trust, Ameriden brought it to the professional market in 1995, it’s the only brand used in US case studies and it is standardized. EXTRA: The vast majority of tests performed with Rhodiola rosea showed improved bodily functions, especially performance (mental and physical). There are also over 143 published articles related to studies with Rhodiola rosea on PubMed. Here are just a few:

Rhodiola Rosea PubMed References

Clinical Trials

Contemporary Standardized Methods

Pharmacodynamics

Pharmacokinetics (ADME)

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9410196&dopt=Abstract

Genetics & Molecular Biology

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9162281&dopt=Abstract

Animal Studies

Sugar The Sweet Deception

admin — Thu, 18 Mar 2010 01:02:48 +0000

Sugar

The Sweet Deception

Sugar is an informal term for a class of edible crystalline substances, mainly sucrose, lactose, and fructose] characterized by a sweet flavor. In food, sugar almost exclusively refers to sucrose, which primarily comes from sugar cane and sugar beet. Other sugars are used in industrial food preparation, but are usually known by more specific names—glucose, fructose or fruit sugar, high fructose corn syrup, etc.

Sugar is also a generic term used to identify simple carbohydrates, which includes monosaccharides such as fructose, glucose and galactose; and disaccharides such as maltose and sucrose (white table sugar).

When fructose is the primary monosaccharide, the glycemic index registers as healthier, since this simple sugar is slowly absorbed in the gut, then converted to glucose in the liver. This allows food to be more time released,” which offers a more gradual rise and fall in blood-glucose levels.

If glucose is the primary monosaccharide, then the glycemic index will be higher and less healthy for the individual. As this monosaccharide is broken down in digestion, the glucose is pumped across the intestinal wall directly into the bloodstream which rapidly raises blood-glucose levels.

Excessive consumption of sugar has been associated with increased incidences of type 2 diabetes, obesity and tooth decay There’s also a huge list of other conditions in which sugar is a key component to the cause. Sugar consumption varies from country to country; Brazil has the highest per capita production and India the highest per-country consumption.

Sugar was not plentiful or cheap in early times—honey was more often used for sweetening. More recently it is manufactured in very large quantities in many countries, largely from sugar cane and sugar beet.

The 1997 American Diabetes Association blood-glucose standards considers126 mg glucose/dL blood or greater to be diabetic; 111 to 125 mg/dL is impaired glucose tolerance and less than 110 mg/dL is considered normal. Prior civilizations were estimated to have generated blood glucose levels between 60 and 90 mg/dL.

With that said, today’s high-sugar diets are having unhealthy effects as far as blood-sugar is concerned. Excess blood glucose may initiate yeast overgrowth, blood vessel deterioration, heart disease and other health conditions. Sugar consumption is a serious problem.

Nancy Appleton, Ph.D and author of the book “Lick the Sugar Habit,” lists 76 reasons why sugar is the sweet deception that could ruin your health:

Sugar can suppress your immune system and impair your defenses against infectious disease.^1,2
Sugar upsets the mineral relationships in your body: causes chromium and copper deficiencies and interferes with absorption of calcium and magnesium. ^3,4,5,6
Sugar can cause can cause a rapid rise of adrenaline, hyperactivity, anxiety, difficulty concentrating, and crankiness in children.^7,8
Sugar can produce a significant rise in total cholesterol, triglycerides and bad cholesterol and a decrease in good cholesterol.^9,10,11,12
Sugar causes a loss of tissue elasticity and function.¹³
Sugar feeds cancer cells and has been connected with the development of cancer of the breast, ovaries, prostate, rectum, pancreas, biliary tract, lung, gallbladder and stomach.^{14,15,16,17,18,19,20}
Sugar can increase fasting levels of glucose and can cause reactive hypoglycemia.^21,22
Sugar can weaken eyesight.²³
Sugar can cause many problems with the gastrointestinal tract including: an acidic digestive tract, indigestion, malabsorption in patients with functional bowel disease, increased risk of Crohn’s disease, and ulcerative colitis.^{24,25,26,27,28}
Sugar can cause premature aging.²⁹
Sugar can lead to alcoholism.³⁰
Sugar can cause your saliva to become acidic, tooth decay, and periodontal disease.^31,32,33
Sugar contributes to obesity.³⁴
Sugar can cause autoimmune diseases such as: arthritis, asthma, multiple sclerosis.^35,36,37
Sugar greatly assists the uncontrolled growth of Candida Albicans (yeast infections)³⁸
Sugar can cause gallstones.³⁹
Sugar can cause appendicitis.⁴⁰
Sugar can cause hemorrhoids.⁴¹
Sugar can cause varicose veins.⁴²
Sugar can elevate glucose and insulin responses in oral contraceptive users.⁴³
Sugar can contribute to osteoporosis.⁴⁴
Sugar can cause a decrease in your insulin sensitivity thereby causing an abnormally high insulin levels and eventually diabetes.^45,46,47
Sugar can lower your Vitamin E levels.⁴⁸
Sugar can increase your systolic blood pressure.⁴⁹
Sugar can cause drowsiness and decreased activity in children.⁵⁰
High sugar intake increases advanced glycation end products (AGEs)(Sugar molecules attaching to and thereby damaging proteins in the body).⁵¹
Sugar can interfere with your absorption of protein.⁵²
Sugar causes food allergies.⁵³
Sugar can cause toxemia during pregnancy.⁵⁴
Sugar can contribute to eczema in children.⁵⁵
Sugar can cause atherosclerosis and cardiovascular disease.^56,57
Sugar can impair the structure of your DNA.⁵⁸
Sugar can change the structure of protein and cause a permanent alteration of the way the proteins act in your body.^59,60
Sugar can make your skin age by changing the structure of collagen.⁶¹
Sugar can cause cataracts and nearsightedness.^62,63
Sugar can cause emphysema.⁶⁴
High sugar intake can impair the physiological homeostasis of many systems in your body.⁶⁵
Sugar lowers the ability of enzymes to function.⁶⁶
Sugar intake is higher in people with Parkinson’s disease.⁶⁷
Sugar can increase the size of your liver by making your liver cells divide and it can increase the amount of liver fat.^68,69
Sugar can increase kidney size and produce pathological changes in the kidney such as the formation of kidney stones.^70,71
Sugar can damage your pancreas.⁷²
Sugar can increase your body’s fluid retention.⁷³
Sugar is enemy #1 of your bowel movement.⁷⁴
Sugar can compromise the lining of your capillaries.⁷⁵
Sugar can make your tendons more brittle.⁷⁶
Sugar can cause headaches, including migraines.⁷⁷
Sugar can reduce the learning capacity, adversely affect school children’s grades and cause learning disorders.^78,79
Sugar can cause an increase in delta, alpha, and theta brain waves which can alter your mind’s ability to think clearly.⁸⁰
Sugar can cause depression.⁸¹
Sugar can increase your risk of gout.⁸²
Sugar can increase your risk of Alzheimer’s disease.⁸³
Sugar can cause hormonal imbalances such as: increasing estrogen in men, exacerbating PMS, and decreasing growth hormone.^84,85,86,87
Sugar can lead to dizziness.⁸⁸
Diets high in sugar will increase free radicals and oxidative stress.⁸⁹
High sucrose diets of subjects with peripheral vascular disease significantly increases platelet adhesion.⁹⁰
High sugar consumption of pregnant adolescents can lead to substantial decrease in gestation duration and is associated with a twofold increased risk for delivering a small-for-gestational-age (SGA) infant.^91,92
Sugar is an addictive substance.⁹³
Sugar can be intoxicating, similar to alcohol.⁹⁴
Sugar given to premature babies can affect the amount of carbon dioxide they produce.⁹⁵
Decrease in sugar intake can increase emotional stability.⁹⁶
Your body changes sugar into 2 to 5 times more fat in the bloodstream than it does starch.⁹⁷
The rapid absorption of sugar promotes excessive food intake in obese subjects.⁹⁸
Sugar can worsen the symptoms of children with attention deficit hyperactivity disorder (ADHD).⁹⁹
Sugar adversely affects urinary electrolyte composition.¹⁰⁰
Sugar can slow down the ability of your adrenal glands to function.¹⁰¹
Sugar has the potential of inducing abnormal metabolic processes in a normal healthy individual and to promote chronic degenerative diseases.¹⁰²
I.V.s (intravenous feedings) of sugar water can cut off oxygen to your brain.¹⁰³
Sugar increases your risk of polio.¹⁰⁴
High sugar intake can cause epileptic seizures.¹⁰⁵
Sugar causes high blood pressure in obese people.¹⁰⁶
In intensive care units: Limiting sugar saves lives.¹⁰⁷
Sugar may induce cell death.¹⁰⁸
In juvenile rehabilitation camps, when children were put on a low sugar diet, there was a 44 percent drop in antisocial behavior.¹⁰⁹
Sugar dehydrates newborns.¹¹⁰
Sugar can cause gum disease.¹¹¹

With all this said, don’t let sugar lead you into the deception that it’s all that good for you, understanding the risks and balance is key to your health. Want to try some good & healthy alternatives to sugar, try Stevia, Rebaudioside-A, Truvia or Lo Han fruit extract.
_____________________________________________________________________________________________________
References

Sanchez, A., et al. Role of Sugars in Human Neutrophilic Phagocytosis, American Journal of Clinical Nutrition. Nov 1973;261:1180_1184. Bernstein, J., al. Depression of Lymphocyte Transformation Following Oral Glucose Ingestion. American Journal of Clinical Nutrition.1997;30:613
Ringsdorf, W., Cheraskin, E. and Ramsay R. Sucrose, Neutrophilic Phagocytosis and Resistance to Disease, Dental Survey. 1976;52(12):46_48.
Couzy, F., et al. “Nutritional Implications of the Interaction Minerals,” Progressive Food and Nutrition Science 17;1933:65-87
Kozlovsky, A., et al. Effects of Diets High in Simple Sugars on Urinary Chromium Losses. Metabolism. June 1986;35:515_518.
Fields, M.., et al. Effect of Copper Deficiency on Metabolism and Mortality in Rats Fed Sucrose or Starch Diets, Journal of Clinical Nutrition. 1983;113:1335_1345.
Lemann, J. Evidence that Glucose Ingestion Inhibits Net Renal Tubular Reabsorption of Calcium and Magnesium. Journal of Clinical Nutrition. 1976 ;70:236_245.
Goldman, J., et al. Behavioral Effects of Sucrose on Preschool Children. Journal of Abnormal Child Psychology.1986;14(4):565_577.
Jones, T. W., et al. Enhanced Adrenomedullary Response and Increased Susceptibility to Neuroglygopenia: Mechanisms Underlying the Adverse Effect of Sugar Ingestion in Children. Journal of Pediatrics. Feb 1995;126:171-7.
Scanto, S. and Yudkin, J. The Effect of Dietary Sucrose on Blood Lipids, Serum Insulin, Platelet Adhesiveness and Body Weight in Human Volunteers, Postgraduate Medicine Journal. 1969;45:602_607.
Albrink, M. and Ullrich I. H. Interaction of Dietary Sucrose and Fiber on Serum Lipids in Healthy Young Men Fed High Carbohydrate Diets. American Journal of Clinical Nutrition. 1986;43:419-428. Pamplona, R., et al. Mechanisms of Glycation in Atherogenesis. Med Hypotheses. Mar 1993;40(3):174-81.
Reiser, S. Effects of Dietary Sugars on Metabolic Risk Factors Associated with Heart Disease. Nutritional Health. 1985;203_216.
Lewis, G. F. and Steiner, G. Acute Effects of Insulin in the Control of Vldl Production in Humans. Implications for The insulin-resistant State. Diabetes Care. 1996 Apr;19(4):390-3 R. Pamplona, M. .J., et al. Mechanisms of Glycation in Atherogenesis. Medical Hypotheses. 1990;40:174-181.
Cerami, A., Vlassara, H., and Brownlee, M. “Glucose and Aging.” Scientific American. May 1987:90. Lee, A. T. and Cerami, A. The Role of Glycation in Aging. Annals of the New York Academy of Science; 663:63-67.
Takahashi, E., Tohoku University School of Medicine, Wholistic Health Digest. October 1982:41:00
Quillin, Patrick, Cancer’s Sweet Tooth, Nutrition Science News. Ap 2000 Rothkopf, M.. Nutrition. July/Aug 1990;6(4).
Michaud, D. Dietary Sugar, Glycemic Load, and Pancreatic Cancer Risk in a Prospective Study. J Natl Cancer Inst. Sep 4, 2002 ;94(17):1293-300.
Moerman, C. J., et al. Dietary Sugar Intake in the Etiology of Biliary Tract Cancer. International Journal of Epidemiology. Ap 1993.2(2):207-214.
The Edell Health Letter. Sept 1991;7:1.
De Stefani, E.”Dietary Sugar and Lung Cancer: a Case control Study in Uruguay.” Nutrition and Cancer. 1998;31(2):132_7.
Cornee, J., et al. A Case-control Study of Gastric Cancer and Nutritional Factors in Marseille, France. European Journal of Epidemiology 11 (1995):55-65.
Kelsay, J., et al. Diets High in Glucose or Sucrose and Young Women. American Journal of Clinical Nutrition. 1974;27:926_936. Thomas, B. J., et al. Relation of Habitual Diet to Fasting Plasma Insulin Concentration and the Insulin Response to Oral Glucose, Human Nutrition Clinical Nutrition. 1983; 36C(1):49_51.
Dufty, William. Sugar Blues. (New York:Warner Books, 1975).
Acta Ophthalmologica Scandinavica. Mar 2002;48;25. Taub, H. Ed. Sugar Weakens Eyesight, VM NEWSLETTER;May 1986:06:00
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Yudkin, J. Sweet and Dangerous.(New York:Bantam Books,1974) 129
Cornee, J., et al. A Case-control Study of Gastric Cancer and Nutritional Factors in Marseille, France, European Journal of Epidemiology. 1995;11
Persson P. G., Ahlbom, A., and Hellers, G. Epidemiology. 1992;3:47-52.
Jones, T. W., et al. Enhanced Adrenomedullary Response and Increased Susceptibility to Neuroglygopenia: Mechanisms Underlying the Adverse Effect of Sugar Ingestion in Children. Journal of Pediatrics. Feb 1995;126:171-7.
Lee, A. T.and Cerami A. The Role of Glycation in Aging. Annals of the New York Academy of Science.1992;663:63-70.
Abrahamson, E. and Peget, A. Body, Mind and Sugar. (New York: Avon, 1977.}
Glinsmann, W., Irausquin, H., and Youngmee, K. Evaluation of Health Aspects of Sugar Contained in Carbohydrate Sweeteners. F. D. A. Report of Sugars Task Force. 1986:39:00 Makinen K.K.,et al. A Descriptive Report of the Effects of a 16_month Xylitol Chewing_gum Programme Subsequent to a 40_month Sucrose Gum Programme. Caries Research. 1998; 32(2)107_12.
Glinsmann, W., Irausquin, H., and K. Youngmee. Evaluation of Health Aspects of Sugar Contained in Carbohydrate Sweeteners. F. D. A. Report of Sugars Task Force.1986;39:36_38.
Appleton, N. New York: Healthy Bones. Avery Penguin Putnam:1989.
Keen, H., et al. Nutrient Intake, Adiposity, and Diabetes. British Medical Journal. 1989; 1:00 655_658
Darlington, L., Ramsey, N. W. and Mansfield, J. R. Placebo Controlled, Blind Study of Dietary Manipulation Therapy in Rheumatoid Arthritis, Lancet. Feb 1986;8475(1):236_238.
Powers, L. Sensitivity: You React to What You Eat. Los Angeles Times. (Feb. 12, 1985). Cheng, J., et al. Preliminary Clinical Study on the Correlation Between Allergic Rhinitis and Food Factors. Lin Chuang Er Bi Yan Hou Ke Za Zhi Aug 2002;16(8):393-396.
Erlander, S. The Cause and Cure of Multiple Sclerosis, The Disease to End Disease.” Mar 3, 1979;1(3):59_63.
Crook, W. J. The Yeast Connection. (TN:Professional Books, 1984).
Heaton, K. The Sweet Road to Gallstones. British Medical Journal. Apr 14, 1984; 288:00:00 1103_1104. Misciagna, G., et al. American Journal of Clinical Nutrition. 1999;69:120-126.
Cleave, T. The Saccharine Disease. (New Canaan, CT: Keats Publishing, 1974).
Ibid.
Cleave, T. and Campbell, G. (Bristol, England:Diabetes, Coronary Thrombosis and the Saccharine Disease: John Wright and Sons, 1960).
Behall, K. Influ ence of Estrogen Content of Oral Contraceptives and Consumption of Sucrose on Blood Parameters. Disease Abstracts International. 1982;431437.
Tjäderhane, L. and Larmas, M. A High Sucrose Diet Decreases the Mechanical Strength of Bones in Growing Rats. Journal of Nutrition. 1998:128:1807_1810.
Beck, Nielsen H., Pedersen O., and Schwartz S. Effects of Diet on the Cellular Insulin Binding and the Insulin Sensitivity in Young Healthy Subjects. Diabetes. 1978;15:289_296 .
Sucrose Induces Diabetes in Cat. Federal Protocol. 1974;6(97). diabetes
Reiser, S., et al. Effects of Sugars on Indices on Glucose Tolerance in Humans. American Journal of Clinical Nutrition. 1986;43:151-159.
Journal of Clinical Endocrinology and Metabolism. Aug 2000
Hodges, R., and Rebello, T. Carbohydrates and Blood Pressure. Annals of Internal Medicine. 1983:98:838_841.
Behar, D., et al. Sugar Challenge Testing with Children Considered Behaviorally Sugar Reactive. Nutritional Behavior. 1984;1:277_288.
Furth, A. and Harding, J. Why Sugar Is Bad For You. New Scientist. Sep 23, 1989;44.
Simmons, J. Is The Sand of Time Sugar? LONGEVITY. June 1990:00:00 49_53.
Appleton, N. New York: LICK THE SUGAR HABIT. Avery Penguin Putnam:1988. allergies
Cleave, T. The Saccharine Disease: (New Canaan Ct: Keats Publishing, Inc., 1974).131.
Ibid. 132
Pamplona, R., et al. Mechanisms of Glycation in Atherogenesis. Medical Hypotheses . 1990:00:00 174_181.
Vaccaro O., Ruth, K. J. and Stamler J. Relationship of Postload Plasma Glucose to Mortality with 19 yr Follow up. Diabetes Care. Oct 15,1992;10:328_334. Tominaga, M., et al, Impaired Glucose Tolerance Is a Risk Factor for Cardiovascular Disease, but Not Fasting Glucose. Diabetes Care. 1999:2(6):920-924.
Lee, A. T. and Cerami, A. Modifications of Proteins and Nucleic Acids by Reducing Sugars: Possible Role in Aging. Handbook of the Biology of Aging. (New York: Academic Press, 1990.).
Monnier, V. M. Nonenzymatic Glycosylation, the Maillard Reaction and the Aging Process. Journal of Gerontology 1990:45(4):105_110.
Cerami, A., Vlassara, H., and Brownlee, M. Glucose and Aging. Scientific American. May 1987:00:00 90
Dyer, D. G., et al. Accumulation of Maillard Reaction Products in Skin Collagen in Diabetes and Aging. Journal of Clinical Investigation. 1993:93(6):421_22.
Veromann, S.et al.”Dietary Sugar and Salt Represent Real Risk Factors for Cataract Development.” Ophthalmologica. 2003 Jul-Aug;217(4):302-307.
Goulart, F. S. Are You Sugar Smart? American Fitness. March_April 1991:00:00 34_38. Milwakuee, WI
Monnier, V. M. Nonenzymatic Glycosylation, the Maillard Reaction and the Aging Process. Journal of Gerontology. 1990:45(4):105_110.
Ceriello, A. Oxidative Stress and Glycemic Regulation. Metabolism. Feb 2000;49(2 Suppl 1):27-29.
Appleton, Nancy. New York; Lick the Sugar Habit. Avery Penguin Putnam, 1988 enzymes
Hellenbrand, W. Diet and Parkinson’s Disease. A Possible Role for the Past Intake of Specific Nutrients. Results from a Self-administered Food-frequency Questionnaire in a Case-control Study. Neurology. Sep 1996;47(3):644-650.
Goulart, F. S. Are You Sugar Smart? American Fitness. March_April 1991:00:00 34_38.
Ibid.
Yudkin, J., Kang, S. and Bruckdorfer, K. Effects of High Dietary Sugar. British Journal of Medicine. Nov 22, 1980;1396.
Blacklock, N. J., Sucrose and Idiopathic Renal Stone. Nutrition and Health. 1987;5(1-2):9- Curhan, G., et al. Beverage Use and Risk for Kidney Stones in Women. Annals of Internal Medicine. 1998:28:534-340.
Goulart, F. S. Are You Sugar Smart? American Fitness. March_April 1991:00:00 34_38. Milwakuee, WI,:
Ibid. fluid retention
Ibid. bowel movement
Ibid. compromise the lining of the capillaries
Nash, J. Health Contenders. Essence. Jan 1992; 23:00 79_81.
Grand, E. Food Allergies and Migraine.Lancet. 1979:1:955_959.
Schauss, A. Diet, Crime and Delinquency. (Berkley Ca; Parker House, 1981.)
Molteni, R, et al. A High-fat, Refined Sugar Diet Reduces Hippocampal Brain-derived Neurotrophic Factor, Neuronal Plasticity, and Learning. NeuroScience. 2002;112(4):803-814.
Christensen, L. The Role of Caffeine and Sugar in Depression. Nutrition Report. Mar 1991;9(3):17-24.
Ibid,44
Yudkin, J. Sweet and Dangerous.(New York:Bantam Books,1974) 129
Frey, J. Is There Sugar in the Alzheimer’s Disease? Annales De Biologie Clinique. 2001; 59 (3):253-257.
Yudkin, J. Metabolic Changes Induced by Sugar in Relation to Coronary Heart Disease and Diabetes. Nutrition and Health. 1987;5(1-2):5-8.
Yudkin, J and Eisa, O. Dietary Sucrose and Oestradiol Concentration in Young Men. Annals of Nutrition and Metabolism. 1988:32(2):53-55.
The Edell Health Letter. Sept 1991;7:1.
Gardner, L. and Reiser, S. Effects of Dietary Carbohydrate on Fasting Levels of Human Growth Hormone and Cortisol. Proceedings of the Society for Experimental Biology and Medicine. 1982;169:36_40.
Journal of Advanced Medicine. 1994;7(1):51-58.
Ceriello, A. Oxidative Stress and Glycemic Regulation. Metabolism. Feb 2000;49(2 Suppl 1):27-29.
Postgraduate Medicine.Sept 1969:45:602-07.
Lenders, C. M. Gestational Age and Infant Size at Birth Are Associated with Dietary Intake among Pregnant Adolescents. Journal of Nutrition. Jun 1997;1113- 1117
Ibid.
Sugar, White Flour Withdrawal Produces Chemical Response. The Addiction Letter. Jul 1992:04:00 Colantuoni, C., et al. Evidence That Intermittent, Excessive Sugar Intake Causes Endogenous Opioid Dependence. Obes Res. Jun 2002 ;10(6):478-488. Annual Meeting of the American Psychological Society, Toronto, June 17, 2001 www.mercola.com/2001/jun/30/sugar.htm
Ibid.
Sunehag, A. L., et al. Gluconeogenesis in Very Low Birth Weight Infants Receiving Total Parenteral Nutrition Diabetes. 1999 ;48 7991_800.
Christensen L., et al. Impact of A Dietary Change on Emotional Distress. Journal of Abnormal Psychology.1985;94(4):565_79.
Nutrition Health Review. Fall 85 changes sugar into fat faster than fat
Ludwig, D. S., et al. High Glycemic Index Foods, Overeating and Obesity. Pediatrics. March 1999;103(3):26-32.
Pediatrics Research. 1995;38(4):539-542. Berdonces, J. L. Attention Deficit and Infantile Hyperactivity. Rev Enferm. Jan 2001;4(1)11-4
Blacklock, N. J. Sucrose and Idiopathic Renal Stone. Nutrition Health. 1987;5(1 & 2):9-
Lechin, F., et al. Effects of an Oral Glucose Load on Plasma Neurotransmitters in Humans. Neurophychobiology. 1992;26(1-2):4-11.
Fields, M. Journal of the American College of Nutrition. Aug 1998;17(4):317_321.
Arieff, A. I. Veterans Administration Medical Center in San Francisco. San Jose Mercury; June 12/86. IVs of sugar water can cut off oxygen to the brain.
Sandler, Benjamin P. Diet Prevents Polio. Milwakuee, WI,:The Lee Foundation for Nutritional Research, 1951
Murphy, Patricia. The Role of Sugar in Epileptic Seizures. Townsend Letter for Doctors and Patients. May, 2001 Murphy Is Editor of Epilepsy Wellness Newsletter, 1462 West 5th Ave., Eugene, Oregon 97402
Stern, N. & Tuck, M. Pathogenesis of Hypertension in Diabetes Mellitus. Diabetes Mellitus, a Fundamental and Clinical Test. 2nd Edition, (PhiladelphiA; A:Lippincott Williams & Wilkins, 2000)943-957.
Christansen, D. Critical Care: Sugar Limit Saves Lives. Science News. June 30, 2001; 159:404.
Donnini, D. et al. Glucose May Induce Cell Death through a Free Radical-mediated Mechanism.Biochem Biohhys Res Commun. Feb 15, 1996:219(2):412-417.
Schoenthaler, S. The Los Angeles Probation Department Diet-Behavior Program: Am Empirical Analysis of Six Institutional Settings. Int J Biosocial Res 5(2):88-89.
Gluconeogenesis in Very Low Birth Weight Infants Receiving Total Parenteral Nutrition. Diabetes. 1999 Apr;48(4):791-800.
Glinsmann, W., et al. Evaluation of Health Aspects of Sugar Contained in Carbohydrate Sweeteners.” FDA Report of Sugars Task Force -1986 39 123 Yudkin, J. and Eisa, O. Dietary Sucrose and Oestradiol Concentration in Young Men. Annals of Nutrition and Metabolism. 1988;32(2):53-5.

Brain Food for a Balanced Brain

admin — Mon, 01 Feb 2010 18:07:15 +0000

-Rhodiola rosea-

For thousands of years, certain civilizations, notably, the Chinese, Egyptians, Indians and Russians have revered herbal remedies for their healing properties. Unfortunately, many countries that used to include herbal medicines put them on the back burner as pharmaceutical drugs rose in popularity. However a renewed interest in alternatives has been revived due to the new findings from their beneficial ingredients. Today research studies published in reputable medical journals such as The Journal of the American Medical Association ^[1] & Wiley’s Psychiatry Second Edition CAM Treatments ^[2] point to the complementary role that herbs play in patients treatment. Yet, of all the herbs noted, the ability of an herb to help the body adapt to stress, improve performance and increase resistance to “the Bad Bugs” is most significant. That herb is Rhodiola rosea from Siberia, a true adaptogen.

Adaptogens help balance our bodily functions via the neurotransmitters of the brain. Once classified as “A Russian Secret” Russian scientists are finally able to bless us with a wealth of information on this wondrous herb. ^[3] Rhodiola rosea, also known as Golden Root, has been used for centuries; in fact Siberian/Russian Rhodiola has over 45 years of clinical studies to back up its legitimacy as a safe and powerful complementary alternative. Let’s discuss one of its many important roles.

Let’s talk serotonin: Serotonin is a monoamine neurotransmitter of which 80% is primarily found in the gastrointestinal (GI) tract and only 20% in the central nervous system (CNS) raphe nuclei of animals. Considering that just the slightest disturbance decreasing serotonin in the raphe nuclei can make a person become obsessive compulsive (OCD), manic depressive or schizophrenic, balancing that little bit of chemical becomes so important. In fact an entire community of doctors now over sees patients on a regular basis to help improve this very problem. SSRIs and other pharmaceutical drugs that alter serotonin levels are the usual treatment of these symptoms. ^[4] However many SSRIs carry unwanted side effects, especially for men.

With so much serotonin in the body you would think we would be home free. However, serotonin in the GI tract cannot cross over the blood-brain barrier, a semi permeable membrane that regulates the passage of certain substances into the brain. Since serotonin is unable to cross over the blood-brain barrier it must be produced directly in the brain. So how is serotonin produced in the brain? An essential amino acid, tryptophan comes into play as serotonin’s raw material that can cross the blood-brain barrier. Tryptophan, when in the brain, is converted to 5-hydroxytryptophan (5-HTP) by the enzyme tryptophan hydroxylase. The final step involves the conversion of 5-HTP to 5-hydroxytryptoptamine (5-HT), otherwise known as serotonin. ^[1]

In humans serotonin levels are affected by diet. An increase in the ratio of tryptophan to phenylalanine and leucine will increase serotonin levels as well. Fruits with a good ratio include dates, papaya and banana. Foods with a lower ratio inhibit the production of serotonin. These include whole wheat and rye bread.^[5] Research also suggests that eating a diet rich in whole grain carbohydrates and low in protein will increase serotonin by secreting insulin, which helps in amino acid competition.^[6] However, increasing insulin for a long period may trigger the onset of insulin resistance, obesity, type 2 diabetes, and lower serotonin levels.

Throughout the body there is a system of checks and balances that work to keep us healthy. Nowhere is this more important than in the control of serotonin production in the brain. Two powerful enzymes called monoamine oxidase and aldehyde dehydrogenase help limit the production of serotonin. Without these two enzymes too much serotonin would be produced which would be just as bad as not enough serotonin. Depression is a consequence of insufficient serotonin levels, this is a fact that shouldn’t be over looked. Remember brain function is dependent upon proper balance. ^[1] Enter Siberian/Russian Rhodiola rosea. Siberian/Russian Rhodiola rosea helps the brain adapt to emotional & physical stressors by balancing serotonin. Do you eat on the go? Are constantly stressed out? Why not give a natural alternative with so much history a try? Rosavin™ or Rosavin Plus®, brain food for a balanced brain.

REFERENCES:

Arctic Root (Rhodiola rosea), Carl Germano, RD. C.S.N., L.D.N. & Zakir Ramazanov. PhD Kensington Publishing Corp. 1999 Introduction
Wiley –PSYCHIATRY Second Edition, CAM TREATMENTS, A. Tasman, J. Kay, J. Lieberman
The Herb that came in from the cold, Peter Jaret, Natural Solutions, 1/01/2005
Wikipedia – http://en.wikipedia.org/wiki/Serotonin
Abu-Jayyab A. “Nutritional Pharmacology Of Sleep & Depression”. SelfGrowth.com. http://www.selfgrowth.com/articles/Nutritional_Pharmacology_of_Sleep_Depression.html. Retrieved 2009-12-02.
Young SN (November 2007). “How to increase serotonin in the human brain without drugs“. J Psychiatry Neurosci 32 (6): 394–9. PMID 18043762

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No part of this article may be reproduced by any means without the expressed written consent of AMERIDEN® International, Inc. 1/6/2010

The Secret of Life

admin — Wed, 06 Jan 2010 22:36:54 +0000

What gives AmeriZyme® its effectiveness? Enzymes!

THE SECRET OF LIFE

……Would You Believe ENZYMES!

How can we make a bold statement like that? The fact is, without Enzymes you just simply DIE! There are three classes of elements your body needs for good health; Vitamins, Minerals and you guessed it, Enzymes. If these three elements were depleted from your body you’d be gone in weeks. While your body does not produce vitamins and minerals, which we receive from our foods, your body does make certain enzymes from its own cells. The word “enzyme” comes from ancient Greece words “N-zye.” This was a process of putting yeast in to dough. The Greeks saw that it converted yeast into the nutritious dough they baked into bread. Science has found that there are two types of enzymes; digestive and systemic. Digestive enzymes contain a broad spectrum Ph and help break down food into micronutrients readily available for your body to absorb while systemic enzymes have many other jobs in the body and are not as broad spectrum Ph, but work as a stimulant in the small intestine to enhance other functions of the body including anti- inflammatory processes.

Every living cell whether produced by animals or plants can and must make enzymes. Since your food is made of cells they therefore contain enzymes. You can even eat foods completely depleted of enzymes and still live. It has baffled science for years about whether it is good to introduce to your body more enzymes, digestive or systemic, in larger quantities than your body already produces. However it has been found that a body needing to produce more necessary enzymes on a continual basis has lead to premature cell exhaustion, which in turn may be a major cause of many illnesses. Currently it has been determined that our foods, which receive there vitamin, mineral and enzymes from the earth, are being depleted at an alarming rate. We are receiving foods that are more and more deficient in bio-available natural plant nutrients as time goes by even though our farmlands are being synthetically simulated with chemicals. This means that supplementation is not only a good idea, but also a must for optimal health.

Here’s a little health tip: Science has found that people age prematurely if they don’t get proper vitamins, minerals and enzymes. What would that mean for you? Do you want to age prematurely? I didn’t think so. If you are approaching 40, start taking your vitamin, minerals and especially enzymes. Why do I stress Enzymes, Science via medical research, have come up with some very startling statistics? If you are getting that Fortyish felling, it has been found that Enzymes of the body tend to become fewer and weaker as we age. This withering process takes place also in animals. Scientists at the world famous Michael Reese Hospital in Chicago found that older people only had 1/30th as much enzymes in their saliva as young folks in their 20’s. Dr. Eckart of Germany discovered after 1,200 urine tests that the enzymes of those over 40 were only half as rich nutrients and enzymes as those in the prime of their life.

Remember I said earlier that Enzymes have many other jobs in the body besides digesting food. In fact every function in the body requires enzymatic action. Just testing the pyloric juices of the stomach for enzyme count would be misleading and a waste of time. You may have enough enzymes to digest your food, but they may be very stretched to complete the rest of your bodily functions that provide quality life. Until now, science has no sure method or knowledge of testing to indicate intercellular enzymatic activity and therefore is rudimentary. What does all this mean to everyday folks like you and me? It means that you and I need to take personal action in preventing vitamin, mineral and enzyme depletion. Supplementing with proper nutrition will help slow down the aging process and provide us with a better quality life.

If you truly want better nutrition, want to slow down the aging process and produce a better quality of life then Enzymes will help you achieve this. But there are a few things you still need to know. Don’t look to commercial foods or drinks for your enzymes. Unlike vitamins and minerals, enzymes are killed 100% by even the slightest heat, boiling, baking, frying, stewing or roasting. However, you will find them in the natural realm, uncooked. You might say “Naturally Packaged” as raw foods. Nibbling on raw foods won’t do it either, you must eat some quantity of them, like a whole apple, not just a slice. How about two carrots, not just those few found in a salad. Please remember that raw fruits and vegetables contain about 90% water. They are filling, but the quantity eaten at any given meal contains only small amounts of enzymes. Chewing or eating raw foods five to ten times a day between meals will accomplish something much more significant. This simply means that increasing raw food intake during the day will have a good effect on your body unless you have a medical condition that prohibits you from eating raw foods.

Another and quite possibly the best way to increase necessary enzymes would be to take concentrated, properly processed plant enzymes that would assure you of optimum benefit & health. These enzymes are usually taken just before or during meals.

Be a wise & careful shopper though, there are many enzyme formulations on the market making outstanding claims. The amount of different enzymes listed on the bottle does not tell you about there activity. Two brands can have the same amount of enzymes listed, however one brand’s enzymes could be completely dead, unsuitable or low in potency which will not accomplish what you intend them to do. Also many enzyme products on the market, which have an effect in an alkaline medium, are destroyed in the stomach acid.

All of AmeriZyme® enzymes are verified live and cover a wide spectrum of Ph conditions. They are obtained from the most reputable cutting edge company when it comes to viable enzymes in America, National Enzyme Corporation, Inc. established in 1932. Coupled with Ameriden’s New Proprietary Uptake system, you may achieve 30% to 40% more nutritional uptake than you would from products three times as expensive. What does this potentially mean to you our valued customers? How about thousands of dollars yearly in better nutrition for you and your family, less health problems, less doctor’s visits and less time off work due to illnesses. We think these are important issues you care about and the reason AmeriZyme® was developed.

AmeriZyme®, Made in America, Made for Results!

Howard Peiper, N.D.

Richard L. Hall, CEO AMERIDEN

December Stress Relief

admin — Thu, 10 Dec 2009 19:26:21 +0000

So are you saying “Ho, Ho, Ho”
OR “No, No, No?”

Tis the Season to be jolly, but for some December can be the Grinch stealing Christmas! So how can we keep stress from robbing our joy and shoveling our dreams into the fire?

The first thing we can do to lessen stress is make a schedule-today, don’t put it off until tomorrow.

Be flexible with time constraints and allow others to be flexible as well. Relax. This is a season; it will pass with or without your help and most mistakes come from hurried decisions.

Take time, stop-breathe, then carry on.

On your own? Don’t go at it alone. Ask others to help you with your errands. Many people would welcome the opportunity to help and share the work load if you would only ask. Then you’ll have a reason to thank them and everyone involved will feel special & needed! Even you!

Start a new Christmas tradition or revive an old one. It may just become your new seasonal favorite.

If you need extra energy or stamina, try a cup of coffee with an added sprinkle of cinnamon, pumpkin, or peppermint spice. If Tea is your treat, green or red Rooibos teas are quick and tasty! Most important of all, don’t forget Rosavin™ or Rosavin Plus®! They can give you sustained energy and increased stamina too. Let Rosavin™ or Rosavin Plus® become your little secret for conquering the long days ahead. Everyone needs a little Ho, Ho, Ho in their life especially during this season.

Here are a few fun family recipes we thought you’d enjoy. They just might inspire you to start that new Holiday Tradition!

Salsa de Mango Negra (Black Mango Salsa)

Ingredients:

1 can Organic (16 oz.) black beans, drained, rinsed
1 pkg. Organic (10 oz.) frozen corn, thawed
1-cup Organic ripe mango (chopped)
1/2 cup red pepper (chopped)
1/3 cup sweet onion (chopped)
1/3 cup cilantro (chopped)
1/4 cup lime juice
4 Tbls Agave Nectar or sweetener of choice

Spices (add to taste a dash of each): Garlic, Sea Salt, Turmeric, Dry Mustard, Oregano, Rosemary, Basil, Thyme, Sage, and White Pepper.

Directions: Mix all ingredients until well blended & cover.

Refrigerate at least 1 hour. You can also make this a day ahead. Keep covered and refrigerated until served

Serve as a topping over your favorite foods or alone with Organic Tortilla chips.

Pomme Joie Fraîche (Apple Delight)

Ingredients:

3 large Organic apple (your favorite)
1 half small Organic lemon
3 Tbl water
2 Tsp Agave Nectar or granulated sugar substitute
See substitutes-Xylitol, Truvia, Lo Han Sweet etc…
Dash of cinnamon

Directions:

Preheat oven to 400° F. Peel core and slice or chop apples. Place apples in small baking dish.
Combine juice of 1/2 small lemon, Agave Nectar or granulated sugar substitute (Xylitol, Truvia, Lo Han Sweet), water and few dashes of cinnamon and then pour over apples.

Make Topping Ingredients:

2 grissini breadstick or Melba toast
1/2 tsp cinnamon
1/4 tsp nutmeg
1/2 tsp pumpkin pie spice or spice of choice

Grind grissini or Melba toast into a powder using a food processor or a coffee grinder. Add dry ingredients together slowly and stir until thoroughly blended. Sprinkle on top of apple filling.

Bake: Cover dish and bake 20 minutes. Remove cover, turn on broiler and broil an additional 1-2 minutes until topping is crisp. Serve immediately.

Crème Fouetté Fait Maison (Homemade Whipped Crème)

Special Topping Treat

Ingredients:

1 pint of Organic Whipping Cream
4 Tbls Pure Vanilla (no sugar added if possible)
¼ C granulated sugar substitute. (Xylitol, Truvia, Lo Han Sweet etc…)

Directions: Blend until cream texture forms. You can add a bit more sweetener if desired. Cover & refrigerate.

It can be prepared several days ahead of time. Use it as an alternative to canned Whip Cream. It’s wonderful added in coffee or your homemade Hot Cocoa. Actually, it’s Divine!

Azúcar Libera el Cacao (Homemade Sugar Free Cocoa)

Ingredients:

2 cups Organic Cocoa powder
¼ C Granulated sugar substitute (Xylitol, Truvia, Lo Han Sweet)
Use more or less depending upon your sweet tooth.
Extra ingredients to add a European flavor: Cinnamon or nutmeg (Amount depends upon your taste)

Directions: Pour dry ingredients into a glass jar. If possible use a jam or jelly jar it makes mixing and storage easier. Shake or blend so that the cocoa & sugar substitute are mixed thoroughly together. Add 1-2 Tbls to 8 oz of hot water & stir.

Top with Crème Fouetté Fait Maison (Homemade Whipped Crème) Enjoy!

Ending thoughts:

If the Grinch can overcome seasonal stress you can too! From Dr. Seuss…

“And the Grinch, with his Grinch-feet ice cold in the snow, stood puzzling and puzzling, how could it be so? It came without ribbons. It came without tags. It came without packages, boxes or bags. And he puzzled and puzzled ’till his puzzler was sore. Then the Grinch thought of something he hadn’t before.
What if Christmas, he thought, doesn’t come from a store. What if Christmas, perhaps, means a little bit more.”

Here’s hoping you have a Wonderful Christmas Season.

Rhodiola Rosea

admin — Fri, 13 Nov 2009 01:08:34 +0000

Article by Abidoff -Fanna
Moscow, Russian Republic

Russian Rhodiola Rosea, gathered from near the Arctic.

WILL ADULTERATION POISON SCIENTIFIC INNOVATION AGAIN?

RHODIOLA ROSEA -Case Study of An Industry Disease. Is There A Cure?

Standardized, clinically potent Rhodiola rosea is a unique and exciting herbal extract that has risen to a level of well-earned consumer excitement that unfortunately is attracting cases of product adulteration, usually justified by misinformation. Apparently the increased popularity of clinically effective forms of Rhodiola rosea now make it a target for counterfeiting with innocuous and ineffective substitutes being sold to a public still too naive to protect itself from low quality alternatives that simply do not work. Unfortunately, this sad tale is all too familiar to experienced innovators in the natural products industry.

The public does not yet fully understand that only true Rhodiola rosea extract containing sufficient standardized levels of its unique active constituents, rosavin, rosin, and rosarin can insure that the consumer is getting the form of the product that works!

Despite its rising popularity, public education about Rhodiola rosea is still in its infancy. That is why articles like this are an essential “preventative medicine” against the abuses and destructive consequences of new product misinformation typically used to justify substitution and adulteration.

The tragedy, of course, is that continuing misinformation will eventually destroy public enthusiasm for the real Rhodiola rosea and diminish its bright future. Regulators and industry critics will once again be warning disappointed consumers that they cannot trust the “unscrupulous and unregulated natural products industry” as a whole! In effect, the recurrent pattern of great products being prematurely discredited and ruine

d by competitive adulteration is a sickness that eats the heart out of the integrity and fundamental health of the entire phytomedicinal industry.

Rhodiola rosea is a perfect case study of how the natural products industry constantly finds itself under attack by critics and regulators because of its historical inability to prevent this type of abuse.

Judge for yourself. here are the facts:

Rhodiola rosea (also known as golden root) is part of the Crassulaceae family of plants, indigenous to the Polar Regions of Eastern Siberia.

The release of information on extraordinary~ health benefits of Rhodiola rosea by the former Soviet Union in the early 1990′ s has dramatically increased interest in this unique medicinal plant. After more than 35 years of intensive research, Russian, Bulgarian and Scandinavian scientists demonstrated that highly active constituents extracted from Rhodiola rosea regulated levels of neurotransmitters in the brain.
‘Pharmacological and medicinal properties of any herbal extracts are a phenomenon strictly specific to unique species of the herbs…’ (Saratikov et al. 1987). Russian botanists have identified nearly 200 species of Rhodiola genus. According to the Russian Pharmacopoeia, key active constituents in Rhodiola rosea that are responsible for its unique pharmacological and medicinal properties are actually complexes of phenylpropanoids : rosavin, rosin and rosarin. If your extract does not contain all of these active constituents then there is no guarantee that what you have been taking will work anywhere as well as clinically true Rhodiola rosea extract that does work.
Some suppliers of so-called “standardized Rhodiola rosea” have standardized their products to 1% salidroside. Critical evaluation of results of recent research clearly shows that the presence of salidroside and its aglycon p-tyrosol is not specific to Rhodiola genus and not the source of Rhodiola’s extensive clinical value. First identified in white willow bark (Salix), salidroside was also found in more than 22 plants, algae and in some bacteria. These active compounds have also been found in virgin olive oil as well as olive leaf extract. The presence of salidroside or p-tyrosol in our diet does have some benefit.For example, P- tyrosol in our diet does have some benefit.
For example, p-tyrosol plays an important role in protecting against LDL oxidation and helping to regulate heart arrhythmia. There are cheaper sources of abundant salidroside available from many other natural products. Rhodiola rosea as well as many other Rhodiola species also contain salidroside and p-tyrosol. But what is unique to the standardized Rhodiola rosea extracts that produced impressive clinical effects is their full specter of pharmacologically active rosavin, rosin and rosarin. The salidroside content alone cannot be used as the objective standard for product evaluation.
The key quality control discovery that allowed us to see the real effectiveness of this amazing extract was in knowing that it had to be standardized to the rosavins content (rosavin, rosin and rosarin) and not according to the salidroside content as presented in Tibetan and Chinese substitutes! Thirty-five years of clinical Research clearly proves that only full potency Rhodiola rosea extract offer full effectiveness, not the salidroside!
The ability of the standardized Rhodiola rosea extract to help the body adapt to stress may lie in its special ability to enhance levels of serotonin, dopamine and other vital neurotransmitters.
Only the Rhodiola rosea extract containing all its key active compounds (rosavin, rosin and rosarin) improves the physical work ability, shorten the recovery period after prolonged muscular workloads, normalizing the parameters of the activity of the cardiovascular system.
During intensive muscular work Rhodiola rosea extract stimulates the production of energy, optimizing the processes of oxidative phosphorilation, activating the phosphorilation of creatine, and stabilizing the mitochondria’s ultra-structure, while stimulating the release of fatty acids from adipose tissue.
Only Rhodiola rosea extract containing all its unique active constituents has shown a positive influence on the higher mobility of the human body; improving mental ability, primarily enhancing the qualitative indicators of the performed work. The effect of “prompt adaptation” arises in the organism with the introduction of the Rhodiola rosea into the central nervous system. Rhodiola rosea prevents the beginning of pathological changes in the organism, caused by immobilizing and emotionally painful stress.
The adaptogenic characteristics of the standardized Rhodiola rosea preparations are displayed in an increase of the resistance of the organism to the action of physical and biological factors. Rhodiola rosea prevents the experimental development of hyper and hypoglycemia, leukocytosis, leucopenia, erythrocytosis, erythropenia and hypoxia.
The proven of effectiveness of Rhodiola rosea extract containing Rosavin and other key compounds in treating depression led Russian scientists to use it in combination with antidepressants. Patients’ general activity along with intellectual and physical productivity increased while duration of hospital stays and side effects normally associated with tricyclic antidepressants decreased. Rhodiola rosea is a safe and effective adjunct to conventional antidepressant therapy.
The Rhodiola rosea preparations increase the anti-tumor resistance of the organism. They significantly inhibit the growth of experimental tumors while decreasing the frequency of their metastases: Also, the life expectancy of animals with tumors is prolonged, decreasing the outcome of spontaneous tumor growth.
The Rhodiola rosea preparations are prescribed as a stimulative remedy for fatigue, for people with an inclination toward asthenia during work, which require increased mental workload, in sports medicine to fight exhaustion occurring during intense muscular work: It also accelerates the recovery processes during intensive training workouts.
In testing the response of exhaustive muscle workloads to Rhodiola rosea extract, it was found that the herb increases the activity of proteolytic enzymes and also significantly elevates the level of RNA and protein in skeletal muscles.

However, many new US Rhodiola products do not establish or maintain true clinical potency in their formulations. Consequently, they will not work and are not worth their price… especially since a clinically potent product is readily available and is verified.

Letting people know about the genetically true Rhodiola rosea extract presents a perfect opportunity to demonstrate the natural product industry’s ability to prevent recurrent threats and set a new standard of validity and integrity. Demand that the truth be told about real Rhodiola rosea extract will insure that consumers get the benefits they expect and pay for; this is critical to preserving the goodwill of our loyal public. Perhaps a more proactive, consumer centered self-help industry is needed to defend and promote objective standards in new product innovations. Participatory public PR campaigns are needed to brighten the image and reality of the natural products industry as a whole. The opportunity exists because the problem persists. Who will stand up for truth in marketing while offering integrity in product innovation? It will be those of us who really care about this industry and who have the principles and power to put our ideals into practice.

Closeup of Rhodiola Rosea flowers

This article presented by:

Dr. Musa T Abidoff MD, Professor of Medicine, President and CEO, Abidoff-Farma & Center of Modern Medicine, Russian Academy of Medicinal Science.Professor Satarov AD, Russian Academy of Medicinal Sciences, Academician Emeritus of Russian Academy of Sciences, President of Medicinal Academy of Sciences, Moscow, Russia.
Professor Krasnov, Russian Academy of Medicinal Sciences, Emeritus Academician of Russian Academy of Sciences, President of Medicinal Academy of Sciences, Moscow, Russia.

From Dis-Ease to Health

admin — Tue, 01 Sep 2009 20:27:09 +0000

Everyone has probably heard the word disease and can relate to it as some kind of plague of mankind, but what I believe people experience over time is ‘Dis-Ease’ with the whole situation of their health. Could it be if they just had a little peace with the process they would heal faster?

As I reflect over more than 40 years of trekking the long & winding road to great health, I cannot help, but realize my ‘assignment’ in life was to get healed; then to help others achieve the same status I have. The knowledge of maintaining or regenerating our health is right at our fingertips, so the question is “do I wait until I am sick or do I take action today.” I didn’t just go into the health care industry I grew into it! It began many years ago when I was a young, know-it-all 20 year old pursuing my dreams, studying philosophy, literature, & the humanities at a local city college while raising 2 daughters and working a 7 day shift in the restaurant business. You know, the normal everyday non-stressful life, yeah, right!

As with most, my symptoms of ‘Dis-Ease’ began in my teenage years when I wasn’t sick, but I was living in denial and I don’t mean the river in Egypt!

I began having blackouts, but was too afraid to tell anyone or do anything about them. That was most uncomfortable. I began seeing doctor after doctor and I took everything they instructed me to take and yet I did not improve; sound familiar? My disease was fast becoming my ‘Dis-Ease.’ I was “shocked” when a doctor told me I had to go to the hospital immediately because I was losing red blood cells.

Losing blood cells, where, I didn’t see or feel them leaving, where were they going, what was happening to me? The loss was from an ulcer big enough to cause such bad gastrointestinal problems that my respiratory system and skin soon gave way to allergies. The list grew quickly; what was happening to my youth? I was overwhelmed with fear, but I couldn’t give up, where would I find an answer to my problem? Weeks of testing and treatment for the bleeding ulcer ultimately cured it, but I was still at ‘Dis-Ease’ with the whole trauma.

Elated that it was gone, I was able to resume my life once again, but went right back to the cause of my ulcer, junk food. I didn’t know food played such a big deal in overall health.

Within 3 days of my junk food diet, the bleeding returned. Suddenly I came to the realization of why I had Dis-Ease, if I continued on the junk food highway, I might not live to see my 30th birthday! So began my journey to health and a ‘Dis-Ease’ Free life. It took me two more years, countless hours of soul searching & divine intervention until I was ready. Peace for some doesn’t come cheap!

I started taking Advanced Nutritional classes that were outside of the traditional realm. Can you imagine how unusual this was in the 70’s? My research & studies put me on a 360º turnaround and I have never looked back! Fortunately, for me this was a perfect time in history and my transition had great help from such mentors as Dr. Bernard Jenson, Dr. Paul Bragg, Dr. Carlton Fredericks & Dr. Benjamin Franks. I also had the privileged to have met & learned from Dr. Jonathan Wright, Dr. David Williams, Weston Price, Jack Challen, Dr. Robert Jay Rowen & Dr. Sherry Rogers to name a few. Few! That’s a whole lot of great advice.

Now let’s fast-forward 12 years, I was juicing daily, eating healthy & feeling fantastic when the dietary supplement market exploded. I knew I had to share what I learned with others so I started my own company “Vital Nutrients.” I promised myself years ago that when I started I would only work with companies who had integrity, credibility and manufactured a high quality product and I have kept my promise all along. As a result, my business continues to bring me great joy and wonderful clients who I am able to help with their health concerns.

Sometimes I feel like the “Natural Nutritional” version of Detective Colombo, but in this distinctive way, I am able to also connect with a unique variety of cliental. My clients are faithful because of my deep commitment to them and the high quality products I carry. Some of my favorites are “The Original Olive Leaf Extract” & “Rosavin Plus” by Ameriden International, Inc. It also helps that I personally use these products; I will continue to keep them as part of my daily regime and I know my clients do as well.

Our society may be caught up in the Big Pharma & the Alice in Wonderland paradigm of modern medicine, which has its place, but a healthy body & mind at peace brings homeostasis, there is nothing like it, may you all find it.

Sincerely Ron Pellegrini

Origins to Art

admin — Wed, 15 Jul 2009 16:45:05 +0000

Origins to Art

I am Tricia Meteer, professional photographer, artist & entrepreneur. I have a secret to share with you and I didn’t expect to find it at work.

It all started seven months ago. I was an executive with Origins and the Estee Lauder Corporation; hopping from one airplane to the next, crisscrossing time zones and hardly getting enough sleep. If you’re working for a living you can probably identify with this and how hard it is to balance a social and family life without feeling like a ping pong ball.

This combination was constantly fatiguing me as I would have to arrive on location with a smile on my face, ready to motivate, educate & lead 50+ employees then work with the clients too. To say the least my life was challenging and keeping stress in check became part of my life’s everyday diet.

It wasn’t until Origins developed a wonderful new skin care collection called Youthtopia that I began hearing about Rhodiola rosea. Just before Origins launched the product we were each given a bottle of Ameriden’s Rhodiola rosea product called Rosavin Plus. It was first on the market in the US and well researched by doctors Richard P. Brown & Patricia Gerbarg who had used it in their medical case studies for over five years. My life was about to change for the better! I have to admit, I was skeptical.

Soon all of us at Origins were experiencing the wonderful effects of this adaptive herb both physically & mentally. Wow! What a difference it made! Rosavin Plus became my secret stress buster and I still use it to this very day.

Like so many, I became confident that life would continue as usual until I was faced with a work change brought on by the times we live in. Origins had been my life for 9 years. Little did I know the change in work would allow me to become the artist I was always meant to be.

Today I am an entrepreneur, owning a fine art and portrait photography company called Equinox Photo, based in Fallbrook, California. I balance my work with riding & training my young horses. Part of my photo client base consists of the equestrian community and I am once again involved in traveling to shows and maneuvering around 1200 pound horses with riders on challenging courses to get those prestigious shots. What a great career change, but not without some adjustments.

Like many artists, I found myself most creative late at night. The switch in professions caused me to experience fatigue in a whole different way, especially when I often have to work extremely long days. It was then that I decided to try another Ameriden product called EZ energy, which still contained my secret ingredient (Rhodiola rosea) plus four other Adaptogens. After the first day I felt like the energizer bunny, it gave me the extra stamina and boost my body needed and to be completely honest I became more focused and ready for anything my new career threw my way.

My stamina increased so much that my husband who was training for a triathlon, took notice and gave it a try hoping to boost his workout level. Not only did his workouts improve, but also his recovery time dropped with better results. EZ Energy came through for both of us.

I love EZ Energy because it does not give me the usual jitters that come with so many energy supplements on the market. This is essential for me since a steady hand, clear mind, & quick reaction time are a must in fine art photography! We usually shoot on outside locations, which involve hauling heavy and sometimes bulky equipment to beautiful and remote places like cliffs or isolated beaches. You’ll find me frequently in the water, all for the sake of art, but no worries I still take my secrets with me. Rosavin Plus & EZ Energy should be in every professional’s bag!

Thanks Ameriden!

RESOURCES

Online shop: www.equinoxphoto.etsy.com
Website and portfolio: www.equinoxphoto.us

Ameriden HealthSpot

The Truth About Olive Leaf Extract

“Calcium elenolate is not in Olive Leaf Extract!”

Olive Leaf Extract is one of the most amazing herbal extracts…but what a lot of confusion has come with it.

About the Author:

References

Other Sources

Additional Olive Leaf Extract References and Research

How Fresh Are Your Dietary Supplements?

Adaptogens & Medicine

Rhodiola Rosea PubMed References

Sugar The Sweet Deception

Sugar

Brain Food for a Balanced Brain

-Rhodiola rosea-

The Secret of Life

December Stress Relief

So are you saying “Ho, Ho, Ho” OR “No, No, No?”

Here are a few fun family recipes we thought you’d enjoy. They just might inspire you to start that new Holiday Tradition!

Salsa de Mango Negra (Black Mango Salsa)

Pomme Joie Fraîche (Apple Delight)

Crème Fouetté Fait Maison (Homemade Whipped Crème)

Special Topping Treat

Azúcar Libera el Cacao (Homemade Sugar Free Cocoa)

Ending thoughts:

If the Grinch can overcome seasonal stress you can too! From Dr. Seuss…

Here’s hoping you have a Wonderful Christmas Season.

Rhodiola Rosea

From Dis-Ease to Health

Origins to Art

Origins to Art

RESOURCES

So are you saying “Ho, Ho, Ho”
OR “No, No, No?”