News & Articles - Rhodiola Rosea
Doctors Specification Sheet
ROSAVIN
DESCRIPTION:
Rosavin capsules contain: Pure Siberian Rhodiola rosea (Standardized
to 3%) 100mg.
What is Rosavin? Rosavin is a “Proprietarily Processed”
form of Siberian Rhodiola rosea utilizing Dr. Zakir Ramazanov’s
extraction method. In 1999 Rosavin was the first Siberian Rhodiola
rosea product to emerge in America and to date the only form of
Siberian Rhodiola rosea to have ever been used in US case studies.
It‘s Freeze-Dried method produces a form of Siberian Rhodiola
rosea that demonstrates a two-fold superiority in prolonging physical
exertion in animal studies. (1a). Rosavin is chemically specific
and contains bioactive Rosavin, Rosin, Rosarin and Salidroside as
key actives. (1b,c,d). It also contains Rosiridol as a key active
Aglycon and Rosiridin as a key Mono-Terpene which produce a specific
chemical finger print under phyto-spectrography. (1e,f,g)
The primary chemical structures are as follows:
Key Phyto Actives:
Rosavin
Rosin
Rosarin
Salidroside
Key Aglycon and Mono-Terpene:
Rosiridol & Rosiridin
BENEFITS:
Anti-aging, anti-anxiety, anti-fatigue and anti-stress
defense.
CLINICAL DATA:
Rosavin (Siberian Rhodiola rosea) is an adaptogenic compound with
over 35 years of clinical studies. The history of its medicinal
usage as a complementary therapy for anxiety, stress and fatigue
continues to be discovered (2a,b,c,d) and dates back well over 300
years. Rosavin (Siberian Rhodiola rosea) has been proven clinically
safe and non-toxic even at doses 200 times higher than normal and
is fast becoming the number one choice when considering an alternative
for the before mentioned physical conditions.(2e,f,g) (2h)
CONTRAINDICATIONS:
Do not use if you have hypertension or hypersensitivity to any of
the ingredients occurs. Stop taking if hypertension or hypersensitivity
occur while taking it in conjunction with other stimulants. Also
it is contraindicated for patients who have been diagnosed with
bipolar disorder.
SIDE EFFECTS:
Occasional agitation, intense dreams, headaches (rare).
DRUG INTERACTIONS:
No adverse interactions with prescription medications or with other
herbal products have been observed.
PREGNANT AND NURSING MOTHERS:
To date, no controlled scientific studies have examined the effects
of Siberian Rhodiola rosea in women who are either pregnant or nursing.
CHILDREN:
While Rosavin has a long historical safety record, no controlled
studies have been performed to determine the safety or effectiveness
in pediatric patents under 6 years of age.
OVERDOSE AND TREATMENT OF OVERDOSE:
No reports of overdose have been recorded, but if you suspect that
you have over dosed, stop taking this product, call your healthcare
practitioner and drink plenty of water.
SUGGUESSED USAGE:
For adults, as a dietary supplement, one capsule 20-30 minutes before
breakfast. If the desired effect has not occurred in three days
add a second capsule 20-30 minutes before lunch. Take with plenty
of water. Requirements may vary and should be individualized. In
all cases, consult your healthcare provider before taking any additional
supplementation.
HOW SUPPLIED:
Rosavin comes in 60 count bottles. Each Rosavin capsule contains
100mg of a standardized 3% purified “Proprietarily Processed”
Siberian Rhodiola rosea. Each capsule is Vegetarian friendly and
does not contain any animal by products. Each capsule also contains
purified brown rice flour as a filler.
REFRENCES:
- 1a Experimental Biology and Medicine, 2005, in press
- 1b Dubichev AG, Kurkin BA, Zapesochnaya GG, et al. (1991). Study
of Rhodiola rosea root chemical composition using HPLC. Chemico-Pharmaceutical
Journal. 2:188–193.
- 1c Ganzera M, Yayla Y, Khan IA. (2001). Analysis of the marker
compounds of Rhodiola rosea L. (golden root) by reversed phase
high performance liquid chromatography. Chem Pharm Bull (Tokyo).
49(4):465–467.
- 1d Germano C, Ramazanov Z, Bernal Suarez M. (1999). Arctic Root
(Rhodiola Rosea): The Powerful New Ginseng Alternative. New York:
Kensington Publishing.
- 1e Kurkin VA, Zapesochnaya GG, Kliaznika VG. (1982). Flavonoids
in Rhodiola rosea root and rhizome. I. Tricin glycosides. Chemistry
of Natural Products. 5:581–584.
- 1f Kurkin VA, Zapessochnaya GG, Shavlinski AN. (1984). Flavonoids
of Rhodiola rosea root. Chemistry of Natural Products. 3:390.
- 1g Kurkin VA (1985a). Method of identification of Rhodiola rosea
root. Chemical and Pharmaceutical Journal. 3:185–190.
- 2a Adamchuk LV, Salnik BU. (1971). Effect of Rhodiola rosea
extract and piridrol on metabolism of rats under high muscular
load. Proceedings Institute of Cytology of Russian Academy of
Science; Leningrad. 89–92.
- 2b Adamchuk LV. (1969). Effects of Rhodiola rosea extract on
the process of energetic recovery of rat under intense muscular
workload. Ph D. Dissertation. Tomsk State University and Medical
Institute, Tomsk, Russia.12
- 2c Darbinyan V, Kteyan A, Panossian A, et al. (2000). Rhodiola
rosea in stress induced fatigue—a double blind crossover
study of a standardized extract SHR-5 with a repeated low-dose
regimen on the mental performance of healthy physicians during
night duty. Phytomedicine 7(5): 365–371.
- 2d Panossian, A,Wikman, G, Wagner H. (1999). Plant adaptogens.
III. Earlier and more recent aspects and concepts on their mode
of action. Phytomedicine. 6(4):287–300.
- 2e Spasov AA, Wikman A, Mandrikov V, et al. (2000). A double-blind,
placebo-controlled pilot study of the stimulating and adaptogenic
effect of Rhodiola rosea SHR-5 extract on the fatigue of students
caused by stress during an examination period with a repeated
low-dose regimen. Phytomedicine. 7(2):85–9.
- 2f Spasov AA, Mandrikov VB, Mironova IA (2000) The effect of
the preparation rodakson on the psychophysiological and physical
adaptation of students to an academic load. Exp. Cin. Pharm. 63(1):76-78.
- 2g Stancheva SL., Mosharoff A. (1987). Effect of the extract
of Rhodiola rosea L. on the content of the brain biogenic monoamines.
Proceedings of Bulgarian Academy of Sciences, Medicine. 40:85–87.
- 2h Brown R, Gerbarg P, Ramazanov Z. (2002). Rhodiola rosea.
A Phytomedicinal Overview. HerbalGram ,56:40–52.
If you have any questions please contact us at info@ameriden.com.
This information is intended for informational and educational purposes
only and is not intended to diagnose, cure or prevent any disease. The Food
& Drug Administration has not evaluated the statements within.
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